Emma Bolderson at Queensland University of Technology - Research Interests, Publications & Academic Profile

Emma Bolderson

Senior Research Fellow / Senior Lecturer

Queensland University of Technology

Australia

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Research Interests

Cell Biology

100%

Biochemistry

100%

Cancer Biology

80%

Dna Repair

60%

Targeted Therapy

40%

Molecular Biology

40%

Chromatin Biology

40%

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Recent Grants

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hSSB1: A key regulator of genome stability and potential cancer therapeutic target

Open Date: 2014-01-01

Close Date: 2016-01-01

Articles16

Targeting the hSSB1-INTS3 Interface: A Computational Screening Driven Approach to Identify Potential Modulators

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Year:

2024

Sequence- and Structure-Dependent Cytotoxicity of Phosphorothioate and 2'-O-Methyl Modified Single-Stranded Oligonucleotides.

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Year:

2024

Inhibition of Aurora B kinase (AURKB) enhances the effectiveness of 5-fluorouracil chemotherapy against colorectal cancer cells.

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Year:

2024

Structural investigation of CDCA3‐Cdh1 protein–protein interactions using in vitro studies and molecular dynamics simulation

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Year:

2023

hSSB1 (NABP2/OBFC2B) modulates the DNA damage and androgen-induced transcriptional response in prostate cancer

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Year:

2023

The fructose-bisphosphate, Aldolase A (ALDOA), facilitates DNA-PKcs and ATM kinase activity to regulate DNA double-strand break repair

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Year:

2023

Mono-phosphorylation at Ser4 of barrier-to-autointegration factor (Banf1) significantly reduces its DNA binding capability by inducing critical changes in its local conformation and DNA binding surface

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Year:

2023

Targeting the COMMD4–H2B protein complex in lung cancer

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Year:

2023

Beyond PARP1: The Potential of Other Members of the Poly (ADP-Ribose) Polymerase Family in DNA Repair and Cancer Therapeutics

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Year:

2022

The role of inner nuclear membrane proteins in tumourigenesis and as potential targets for cancer therapy

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Year:

2022

Cell Metabolism and DNA Repair Pathways: Implications for Cancer Therapy

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Year:

2021

Barrier-To-Autointegration-factor (Banf1) modulates DNA double-strand break repair pathway choice via regulation of DNA-dependent kinase (DNA-PK) activity

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Year:

2021

COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks

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Year:

2021

Elevating CDCA3 Levels Enhances Tyrosine Kinase Inhibitor Sensitivity in TKI-Resistant EGFR Mutant Non-Small-Cell Lung Cancer

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Year:

2021

Elevating CDCA3 levels in non-small cell lung cancer enhances sensitivity to platinum-based chemotherapy

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Year:

2021

Identification of Proteins Deregulated by Platinum-Based Chemotherapy as Novel Biomarkers and Therapeutic Targets in Non-Small Cell Lung Cancer.

Article Link

Year:

2021

Collaborators8

Mark Adams

Queensland University of Technology

AUSTRALIA

Luke Guddat

Professor

University of Queensland

AUSTRALIA

Neha S. Gandhi

Queensland University of Technology

AUSTRALIA

Pascal Duijf

Associate Professor

University of South Australia

AUSTRALIA

Kienan Savage

Reader/Group Leader

The Queen's University Belfast

UNITED KINGDOM

Kenneth O'Byrne

Queensland University of Technology

AUSTRALIA

Derek Richard

Queensland University of Technology

AUSTRALIA

Amila Suraweera

Research Fellow/Lecturer

Queensland University of Technology

AUSTRALIA

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