Yitian Zhou at Karolinska Institutet - Research Interests, Publications & Academic Profile

Yitian Zhou

Karolinska Institutet

Sweden

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Research Interests

Biostatistics

80%

Pharmacology

100%

Medical Science

100%

Pharmacogenomic

80%

Personalized Medicine

70%

Genomic

70%

Gwas

50%

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Articles20

Population-scale variability of the human UDP-glycosyltransferase gene family

Article Link

Year:

2024

APF2: an improved ensemble method for pharmacogenomic variant effect prediction

Article Link

Year:

2024

APF2: an improved ensemble method for pharmacogenomic variant effect prediction

Article Link

Year:

2024

Population-specific variations in KCNH2 predispose patients to delayed ventricular repolarization upon dihydroartemisinin-piperaquine therapy

Article Link

Year:

2024

Population-specific variations in KCNH2 predispose patients to delayed ventricular repolarization upon dihydroartemisinin-piperaquine therapy

Article Link

Year:

2024

Next-generation sequencing in pharmacogenomics – fit for clinical decision support?

Article Link

Year:

2024

Meta-analysis of the global distribution of clinically relevant CYP2C8 alleles and their inferred functional consequences

Article Link

Year:

2024

Pharmacogenomics Beyond Single Common Genetic Variants: The Way Forward

Article Link

Year:

2024

Challenges Related to the Use of Next-Generation Sequencing for the Optimization of Drug Therapy

Article Link

Year:

2023

Cross-Ancestry Genome-Wide Association Study Defines the Extended CYP2D6 Locus as the Principal Genetic Determinant of Endoxifen Plasma Concentrations

Article Link

Year:

2023

A paradigm shift in pharmacogenomics: From candidate polymorphisms to comprehensive sequencing

Article Link

Year:

2022

The genetic landscape of major drug metabolizing cytochrome P450 genes—an updated analysis of population-scale sequencing data

Article Link

Year:

2022

Challenges and opportunities associated with rare-variant pharmacogenomics

Article Link

Year:

2022

Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine

Article Link

Year:

2021

Cardiovascular Pharmacogenomics: An Update on Clinical Studies of Antithrombotic Drugs in Brazilian Patients

Article Link

Year:

2021

Computational Tools to Assess the Functional Consequences of Rare and Noncoding Pharmacogenetic Variability

Article Link

Year:

2021

Editorial: Population Pharmacogenomics (PGx): From Variant Identification to Clinical Implementation

Article Link

Year:

2021

Global Frequencies of Clinically Important HLA Alleles and Their Implications For the Cost-Effectiveness of Preemptive Pharmacogenetic Testing

Article Link

Year:

2021

Pharmacogene Sequencing of a Gabonese Population with Severe Plasmodium falciparum Malaria Reveals Multiple Novel Variants with Putative Relevance for Antimalarial Treatment

Article Link

Year:

2021

Pharmacogenomics in the era of next generation sequencing - from byte to bedside

Article Link

Year:

2021

Collaborators5

Erik Eliasson

Karolinska Institutet

SWEDEN

Stefania Koutsilieri

Karolinska Institutet

SWEDEN

Souren Mkrtchian

Karolinska Institutet

SWEDEN

Volker Lauschke

Assistant Professor

Karolinska Institutet

SWEDEN

Gunnar Schulte

Professor

Karolinska Institutet

SWEDEN

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Yitian Zhou

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Research Interests

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Articles20

Population-scale variability of the human UDP-glycosyltransferase gene family

APF2: an improved ensemble method for pharmacogenomic variant effect prediction

APF2: an improved ensemble method for pharmacogenomic variant effect prediction

Population-specific variations in KCNH2 predispose patients to delayed ventricular repolarization upon dihydroartemisinin-piperaquine therapy

Population-specific variations in <i>KCNH2</i> predispose patients to delayed ventricular repolarization upon dihydroartemisinin-piperaquine therapy

Next-generation sequencing in pharmacogenomics – fit for clinical decision support?

Meta-analysis of the global distribution of clinically relevant <i>CYP2C8</i> alleles and their inferred functional consequences

Pharmacogenomics Beyond Single Common Genetic Variants: The Way Forward

Challenges Related to the Use of Next-Generation Sequencing for the Optimization of Drug Therapy

Cross-Ancestry Genome-Wide Association Study Defines the Extended <i>CYP2D6</i> Locus as the Principal Genetic Determinant of Endoxifen Plasma Concentrations

A paradigm shift in pharmacogenomics: From candidate polymorphisms to comprehensive sequencing

The genetic landscape of major drug metabolizing cytochrome P450 genes—an updated analysis of population-scale sequencing data

Challenges and opportunities associated with rare-variant pharmacogenomics

Rare genetic variability in human drug target genes modulates drug response and can guide precision medicine

Cardiovascular Pharmacogenomics: An Update on Clinical Studies of Antithrombotic Drugs in Brazilian Patients

Computational Tools to Assess the Functional Consequences of Rare and Noncoding Pharmacogenetic Variability

Editorial: Population Pharmacogenomics (PGx): From Variant Identification to Clinical Implementation

Global Frequencies of Clinically Important HLA Alleles and Their Implications For the Cost-Effectiveness of Preemptive Pharmacogenetic Testing

Pharmacogene Sequencing of a Gabonese Population with Severe Plasmodium falciparum Malaria Reveals Multiple Novel Variants with Putative Relevance for Antimalarial Treatment

Pharmacogenomics in the era of next generation sequencing - from byte to bedside

Collaborators5

Erik Eliasson

Stefania Koutsilieri

Souren Mkrtchian

Volker Lauschke

Gunnar Schulte

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