The Department of Physics, Chemistry and Pharmacy at the University of Southern Denmark (SDU) in Odense is offering a postdoctoral position in Organic Chemistry, focusing on the design and semi-synthesis of novel antibacterial agents. This opportunity is part of a Novo Nordisk Foundation project dedicated to the semi-synthesis of pleuromutilin derivatives as new antibiotics, with the goal of identifying compounds that specifically target multi-resistant Gram-negative pathogens. The research will involve introducing new modifications to the natural product Pleuromutilin using semi-synthetic approaches to generate derivatives with improved activity and decreased resistance potential.

The successful candidate will join a Chemistry research group and work under the supervision of Professor Poul Nielsen. The position is available from March 1st, 2026, or soon thereafter, and is initially appointed for 12 months with the possibility of extension. Applicants should hold a Ph.D. in organic chemistry, medicinal chemistry, or a related discipline, and must demonstrate strong expertise in synthetic organic chemistry, including multi-step synthesis. Additional advantages include experience with medicinal chemistry principles, structure-activity relationships (SAR), antibacterial drug design, and purification and analytical techniques. Good interpersonal and communication skills in English are essential for effective interdisciplinary teamwork.

This postdoctoral role offers the chance to contribute to cutting-edge research in antibacterial drug design, with a focus on combating antibiotic resistance. The project is fully funded by the Novo Nordisk Foundation. For more information or to apply, candidates are encouraged to contact Professor Poul Nielsen at [email protected] and visit the official application link. The application deadline is January 21st, 2026.