Diego Muñoz-Torrero at University of Barcelona - Research Interests, Publications & Academic Profile

Diego Muñoz-Torrero

Full Professor of Organic & Medicinal Chemistry

University of Barcelona

Spain

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Research Interests

Biochemistry

40%

Pharmaceutical Chemistry

100%

Chemical Biology

90%

Neuropharmacology

70%

Mouse Genetics

30%

Protein Chemistry

30%

Enzyme Engineering

20%

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Articles16

Stepwise Structural Simplification of the Dihydroxyanthraquinone Moiety of a Multitarget Rhein-Based Anti-Alzheimer Lead to Improve Drug Metabolism and Pharmacokinetic Properties

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Year:

2024

Effect of the aggregated protein dye YAT2150 on Leishmania parasite viability

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2024

Acetylcholinesterase: A Versatile Template to Coin Potent Modulators of Multiple Therapeutic Targets

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Year:

2024

Chlorpyrifos Oxon Activates Glutamate and Lysine for Protein Cross-linking

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Year:

2023

A novel rhein-huprine hybrid ameliorates disease-modifying properties in preclinical mice model of Alzheimer's disease exacerbated with high fat diet.

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Year:

2023

A rhein-huprine hybrid protects erythrocyte membrane integrity against Alzheimer’s disease related Aβ(1-42) peptide

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Year:

2023

A Combined Chronic Low-Dose Soluble Epoxide Hydrolase and Acetylcholinesterase Pharmacological Inhibition Promotes Memory Reinstatement in Alzheimer’s Disease Mice Models

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2022

Discovery of Dual Aβ/Tau Inhibitors and Evaluation of Their Therapeutic Effect on a Drosophila Model of Alzheimer’s Disease

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2022

Unveiling the Multitarget Anti-Alzheimer Drug Discovery Landscape: A Bibliometric Analysis

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2022

The protein aggregation inhibitor YAT2150 has potent antimalarial activity in Plasmodium falciparum in vitro cultures

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2022

From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects

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Year:

2021

Clock/Sleep-Dependent Learning and Memory in Male 3xTg-AD Mice at Advanced Disease Stages and Extrinsic Effects of Huprine X and the Novel Multitarget Agent AVCRI104P3

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2021

Protective Role of a Donepezil-Huprine Hybrid against the β-Amyloid (1-42) Effect on Human Erythrocytes

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2021

The Cream of the Crop of the Medicinal Chemistry Section of Molecules—2019

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2021

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–7

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Year:

2020

Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice

Article Link

Year:

2020

Collaborators26

Jussara Amato

University of Naples Federico II

ITALY

George Kokotos

National and Kapodistrian University of Athens

GREECE

Maurizio Pellecchia

Professor

University of California

UNITED STATES

María Isabel Loza García

Professor of Pharmacology with tenure

Universidade de Santiago de Compostela

SPAIN

Amanda Cano

Head of Molecular Biology & Biomarkers program

SPAIN

Christian Griñán Ferré

Assistant Professor

University of Barcelona

SPAIN

Michael Gütschow

University of Bonn

GERMANY

Carles Galdeano

Serra Hunter Lecturer professor

University of Barcelona

SPAIN

Giuseppe Legname

Professor

Scuola Internazionale Superiore di Studi Avanzati

ITALY

Manuela Bartolini

University of Bologna

ITALY

STEFANO MANGANI

Full Professor of Chemistry

University of Siena

ITALY

Miren Ettcheto

Profesor lector

University of Barcelona

SPAIN

Jose Brea

Universidade de Santiago de Compostela

SPAIN

Belén Pérez

Universitat Autònoma de Barcelona (UAB)

SPAIN

Santiago Vazquez

Full professor

University of Barcelona

SPAIN

Oksana Lockridge

Professor

University of Nebraska Medical Center

UNITED STATES

Katalin Prokai-Tatrai

Professor

University of North Texas Health Science Center

UNITED STATES

Ondrej Soukup

University Hospital Hradec Králové

CZECH REPUBLIC

Ivan Kosalec

CROATIA

Ludovic Jean

Full professor

Université de Lorraine Faculté de Pharmacie

FRANCE

Mercè Pallàs

University of Barcelona

SPAIN

Pelayo Camps

Emeritus Professor

University of Barcelona

SPAIN

Yasu-Taka Azuma

JAPAN

Jordi Olloquequi

Lecturer

University of Barcelona

SPAIN

Peter Scott

Associate Professor

University of Michigan

UNITED STATES

Jarkko Rautio

Professor in pharmaceutical chemistry

University of Eastern Finland

FINLAND

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