PhD Position: Connections Between the Nucleus, the Cytoskeleton and Tumorigenesis

This PhD position at Ariel University focuses on investigating the intricate connections between the nucleus, the cytoskeleton, and tumorigenesis, with a particular emphasis on cancer cell migration. The research group, led by Professor Gabi Gerlitz in the Department of Molecular Biology, has made significant advances in understanding how chromatin and microtubule dynamics, as well as the nuclear envelope and actin organization, contribute to cancer development and progression. Recent studies from the group have revealed novel links between these cellular components, as highlighted in several key publications ( Springer , Wiley , MDPI , Frontiers ). The current research aims to elucidate the mechanisms by which the histone methyltransferase SETDB1 influences microtubule dynamics and cellular resistance to chemotherapy, as well as to understand the formation and functional roles of the perinuclear actin rim. This project is ideal for candidates interested in cancer biology, molecular biology, and cell biology, and offers the opportunity to work in a collaborative and supportive research environment. Applicants should possess a successful MSc degree in biological sciences, demonstrate fluency in English, and have hands-on experience with molecular biology or cell biology techniques. The position comes with a full 4-year competitive scholarship, providing financial support throughout the PhD studies. Applications are accepted year-round, and interested candidates are encouraged to contact Prof. Gabi Gerlitz at [email protected] for further information and application procedures. This opportunity is well-suited for highly motivated students eager to contribute to cutting-edge research in cancer cell biology and to develop advanced skills in molecular and cellular techniques. Ariel University provides a dynamic academic setting with access to state-of-the-art facilities and a vibrant scientific community.