PhD in Purification of Advanced Biological Products Using 3D-Printed Structures

This fully funded PhD project at University College London focuses on the purification of advanced biological products, such as viral vectors, using innovative 3D-printed structures. The complexity of emergent biological products presents significant challenges for efficient and scalable manufacturing, often resulting in high costs due to limitations in current purification technologies. This research aims to overcome these barriers by leveraging 3D printing to design and fabricate custom purification materials tailored to the specific needs of complex biologics. The project is based in the Department of Biochemical Engineering, within the 'Recovery of Biological Products' group, and integrates expertise in bioprocessing and advanced imaging techniques to inform the design of new purification materials. Over four years, the doctoral candidate will: (1) demonstrate 3D-printed column purification of model proteins and monoclonal antibodies; (2) tailor designs for optimal purification of advanced products like viral vectors; (3) develop a framework for optimizing purification structures for future biologics; and (4) investigate 3D-printed monoliths for primary recovery and cell therapies. The studentship covers full tuition (with additional support for international students), a tax-free stipend at an enhanced rate (at least £23,466 in 2026/27, increasing annually), and a Research Training Support Grant for project costs, conferences, and travel. Applicants should have a strong background in biochemical engineering, chemical engineering, biotechnology, materials science, or a related field, and an interest in bioprocessing or 3D printing. The application deadline is 5 January 2026. Applications must be submitted via the official UCL EPSRC Doctoral Training portal. For further information or technical queries, contact the DTP Manager at [email protected].