PhD in Developing Sub-millimetric Radioactive Sources for Precision Plaque Brachytherapy Using Electroplating and 3D Printing Technologies Université Laval in Canada

This PhD project at Université Laval focuses on developing sub-millimetric radioactive sources using advanced electroplating and high-resolution 3D printing technologies for precision plaque brachytherapy. Brachytherapy is a form of internal radiotherapy widely used to treat cancers such as breast, prostate, and ocular tumors. The project aims to create highly personalized implants by integrating thin radioactive sources onto biocompatible substrates, enabling clinicians to deliver tailored dose profiles to tumors with greater precision than current methods.

The research is structured around three main objectives: (1) designing arrays of polymeric sub-millimetric substrates via 3D printing for efficient handling and radioisotope plating, (2) developing standardized and reproducible radioactive coatings using surface chemistry, electrochemistry, or physical deposition processes, and (3) assembling these sources onto 3D-printed substrates modeled from patient anatomies to produce prototypes applicable to a range of cancers, including ocular, gynecological, gastrointestinal, nasopharyngeal, and head-and-neck cancers.

The project is conducted within a unique ecosystem at Université Laval, in collaboration with the Centre de Recherche du CHU de Québec (CR-CHUQ-UL) and clinical experts in radiation oncology. The student will work at the interface of medical physics and materials science, contributing to the development of innovative biomaterial technologies and radioactive treatments. The research group is recognized for its expertise in biomedical prostheses and implant development, leveraging advanced 3D-printing capabilities.

Applicants may pursue the PhD through one of two academic paths: Medical Physics and Related Technologies (6 courses × 3 credits) or Materials Engineering (4 courses × 3 credits), leading to career opportunities in medical physics, clinical radiation sciences, implant technologies, and biomedical engineering applied to cancer treatment.

Essential requirements include a Master’s degree in materials science or engineering, surface chemistry, biomedical engineering, engineering physics, applied physics, medical physics, or nuclear science and technology (1st class or upper 2nd class Honours, or equivalent). Candidates must demonstrate a strong academic and research background, experience in 3D printing (FFF, resin printing, or both), motivation for multidisciplinary research, excellent communication and analytical skills, and the ability to work independently. Desirable skills include experience with CAD software, radioisotope handling, surface science, electroplating, and prior research experience. Applicants must meet Université Laval’s PhD eligibility criteria. The main teaching and working language is French, and candidates are expected to learn French within three years.

The position is open to both Canadian and international students. Funding includes a stipend of $27,500/year (tax free at the provincial level, minimum federal income tax), renewable upon demonstrated good progress, supported by a CIHR research grant (2026-2031). Students are responsible for complementary funding for living expenses and medical insurance (for international students). Tuition fees are not covered; details are available at Université Laval Tuition Fees. Applicants with additional funding sources are welcome and encouraged to develop grantmanship skills.

To apply, send your final and interim transcripts, CV, covering letter with referee contact details, supporting statement, and language certificate to Dr Marc-André Fortin ([email protected]). Ensure referee emails are official university/work addresses. Applications are reviewed until May 15, 2026 or until the position is filled. The expected start date is September 2026.

Université Laval is committed to equity, diversity, and inclusion, actively encouraging applicants from diverse backgrounds and career paths. The research group’s recent publications can be found at PubMed 39890553, PubMed 37536742, PubMed 37094373, and ScienceDirect.