This PhD project at the University of York’s Department of Chemistry focuses on the development of dynamic, switchable supramolecular assemblies using ionic bonding—a powerful but underexplored alternative to hydrogen bonding in supramolecular chemistry. Unlike covalent bonds, non-covalent interactions such as ionic bonds are reversible and can be switched on or off by chemical reactions that alter the charge of functional groups. The research aims to create responsive supramolecular structures by synthesizing building blocks capable of reversible charge generation through nucleophilic substitution, proton transfer, and single electron transfer reactions.

The project will utilize advanced techniques including EPR spectroscopy (with access to two spectrometers), NMR, and mass spectrometry to study stable free radicals and the properties of the new assemblies. In the second phase, polyfunctional molecules with switchable ionic groups—such as dendrimers and nanoparticles—will be developed to self-assemble into oligomeric or polymeric materials with tunable properties. The research group offers expertise in supramolecular and nanoscale chemistry, mechanistic chemistry of free radicals, and EPR spectroscopy, providing a rich interdisciplinary training environment. Students will receive comprehensive training in synthetic and physical organic chemistry, analytical methods, and data analysis, as well as transferable skills through the department’s cohort-based training programme.

The department is committed to equality, diversity, and widening participation, with initiatives to support under-represented groups. Funding is available for tuition, stipend, and research costs, with opportunities to attend conferences and external training. Applicants should have or expect to achieve at least a UK upper second class degree in Chemistry or a related subject, and meet English language requirements if applicable.

The application process includes online submission, possible supervisor contact, and panel interviews for shortlisted candidates. The project offers a unique opportunity to contribute to a novel area of supramolecular chemistry and develop a broad skill set in a supportive and inclusive environment.