PhD Position in Neuroscience and Biophysics (TRP Channels in Cerebellum-like Circuits, Drosophila) Medizinische Universität Graz in Austria

The Groschner Lab at the Medizinische Universität Graz is offering a 4-year PhD position focused on the study of TRP channels in cerebellum-like circuits using Drosophila as a model organism. This opportunity is ideal for students interested in neuroscience, biophysics, genetics, and behavioural methods. The lab employs a mechanistic approach to circuit neuroscience, utilizing genetic, functional, and behavioural techniques to manipulate and study neural circuits in a targeted fashion. The fruit fly model is chosen for its simplicity, well-charted connectivity, and the ability to precisely control nervous activity.

The research project centers on mutations in the Trpc3 gene, which encodes the transient receptor potential channel TRPC3, known to cause ataxia in vertebrates. The project aims to investigate the developmental, structural, and functional consequences of these mutations in Drosophila, leveraging the organism's suitability for genetic manipulation and circuit analysis. The Drosophila mushroom body, with its similarities to the vertebrate cerebellum, provides a unique system to study the mechanisms by which TRP channels influence neuronal growth and function. The project will focus on the homologous trp gene in Drosophila and its role in shaping the growth and function of neurons, particularly in mushroom body output neurons (MBONs).

The Groschner Lab fosters an inclusive environment and encourages applications from students with diverse backgrounds. Applicants should have a strong interest in neuroscience, genetics, and behavioural research. Experience with Drosophila or similar model organisms is advantageous. The position is for a 4-year PhD project, but specific funding details are not provided in the announcement. The application deadline is 22 March 2026.

To apply, visit the Groschner Lab website at www.groschner-lab.org/join and follow the application instructions. For further questions, applicants can contact Dr. Lukas Groschner at [email protected]. This is an excellent opportunity for students passionate about neuroscience, biophysics, and genetic research to join a dynamic and supportive research group at a leading Austrian medical university.