The IEO European Institute of Oncology in Milan, Italy, is offering a 3-year fully funded postdoctoral position in the Department of Experimental Oncology, under the supervision of Serena Ghisletti. This opportunity is part of the EP PerMed project, focusing on 'Precision Medicine for Therapy-Related Myeloid Neoplasms.' The research will center on the integration and analysis of multi-omics data (including RNA-seq, ChIP-seq, ATAC-seq) to investigate transcriptional programs, cell heterogeneity, and the interplay between transcriptional circuits and epigenetic states in myeloid neoplasms.

Key responsibilities include evaluating and implementing advanced bulk and single-cell RNA-seq workflows, developing and maintaining sequencing data processing pipelines on high-performance computing systems, and identifying patient-specific signatures by correlating longitudinal single-cell data with clinical outcomes. The position requires a PhD in bioinformatics, computational biology, systems biology, or a related field, with experience in NGS and omics data analysis, strong computational/statistical skills (Unix, Python, R/Bioconductor), and handling large-scale biological datasets. Additional skills in workflow management (Nextflow, Snakemake), single-cell/spatial omics analysis (Seurat, Scanpy), machine learning, AI, and containerization tools (Docker, Singularity) are highly valued.

The successful candidate will join a dynamic team at IEO, contributing to cutting-edge research in precision medicine and oncology. The position is fully funded for three years, with support from the European Partnership for Personalised Medicine. Interested candidates should submit their CV to Serena Ghisletti at [email protected]. For more information, candidates can review the EP PerMed project details and contact the supervisor directly.