The Paul Scherrer Institute (PSI), Switzerland's largest research institute for natural and engineering sciences, invites applications for a PhD Student in Proton Therapy Research. PSI is renowned for its cutting-edge research in future technologies, energy, climate, health innovation, and the fundamentals of nature. The Center for Proton Therapy at PSI has been a global leader in proton-based cancer treatment since 1984, offering a unique environment for interdisciplinary and impactful research. This PhD project focuses on advancing personalized proton therapy for cancer patients. The research aims to develop a mathematical framework that incorporates nano-dosimetric quantities—direct representations of DNA cell damage—into the optimization of proton therapy treatments. By integrating these parameters, the project seeks to improve the prediction of biological effectiveness and to investigate the influence of different proton therapy delivery modalities. The work is highly collaborative, involving partnerships with the University of Zurich and the Cyclotron Centre Bronowice in Krakow, and the successful candidate will be registered as a PhD student at ETH Zurich. Applicants should possess a Master’s degree in physics, mathematics, engineering, or related natural sciences, and demonstrate fluency in English. A strong interest in proton therapy research, mathematical modelling, and programming is essential. The position offers systematic on-the-job training, personal development opportunities, and a supportive, innovative work environment. PSI provides modern employment conditions and infrastructure to help balance work with personal interests or family life. The application deadline is 15 March 2026. Interested candidates should apply online, including the addresses of referees. For further information, Prof. Dr Antony John Lomax can be contacted. This is an excellent opportunity to contribute to the future of cancer treatment in a world-class research setting.

The Paul Scherrer Institute (PSI), Switzerland's largest research institute for natural and engineering sciences, is seeking a Postdoctoral Fellow in proton therapy research. PSI is renowned for its cutting-edge research in future technologies, energy, climate, health innovation, and the fundamentals of nature. The Center for Proton Therapy at PSI has been a global leader in proton-based cancer treatment since 1984, offering innovative radiotherapy modalities to patients. This postdoctoral project focuses on advancing personalized cancer treatment by investigating the biological effects of protons compared to conventional radiotherapy. The research will explore nano-dosimetric quantities as direct representations of DNA cell damage, aiming to improve the prediction of the biological effectiveness of proton therapy. The successful candidate will develop a Monte Carlo model of the PSI scanning Gantry to recalculate a large number of treatment plans, which will then be used for statistical analysis of a retrospective clinical data set. The position is part of a collaborative project involving the University of Zurich and the Cyclotron Centre Bronowice in Krakow, providing opportunities for interdisciplinary and international collaboration. The employment contract is limited to two years, and the institute offers systematic on-the-job training, personal development opportunities, and modern employment conditions to support work-life balance. Applicants should have a PhD in physics, mathematics, engineering, computer science, or related natural sciences, with fluency in English. Experience in medical physics, proton therapy, mathematical modeling, programming, and/or Monte Carlo simulations is advantageous. The application deadline is 15 March 2026. For more information, contact Prof. Dr Antony John Lomax. Applications should be submitted online and include a list of publications and referee addresses. For further details and to apply, visit the official PSI website or the application link provided.