PhD & Postdoctoral Researcher in Synthetic Chemistry for Hyperpolarized MRI

Section Biomedical Imaging (SBMI) at Kiel University and UKSH is seeking PhD and Postdoctoral Researchers in Synthetic Chemistry for a cutting-edge project in hyperpolarized MRI. The research focuses on the development of SABRE/PHIP catalysts and isotope-labeled molecules to advance hyperpolarized NMR and MRI for real-time metabolic imaging, with applications in disease (e.g., cancer) metabolism. The project is led by Prof. Jan-Bernd Hövener, offering mentorship and access to state-of-the-art chemical and magnetic resonance facilities. The core research involves organometallic/organic synthesis of hydrogenation catalysts, ligand optimization, and isotope labeling (13C, 2H), followed by advanced spectroscopic characterization and polarization screening. The interdisciplinary environment provides opportunities to synthesize and optimize hydrogenation catalysts and labeled substrates, perform NMR characterization, and present results at conferences and in scientific journals. Applicants for the PhD track should have a Master's degree in Chemistry or a closely related field with a strong record in synthetic chemistry. Postdoc candidates require a PhD in Organic/Organometallic Chemistry (or closely related) with demonstrated experience in catalyst and/or isotope-labeled molecule synthesis. Experience with air/moisture-sensitive techniques (Schlenk, glovebox) and homogeneous catalysis is preferred. Good English skills, teamwork, and motivation to translate synthesis into hyperpolarization methods for NMR/MRI are essential. Prior knowledge in NMR/MRI is not required. The position offers a 3-year contract (PhD, 75% TV-L 13) or a 2.5-year contract (Postdoc, 100% TV-L 13), with access to advanced imaging and chemical facilities. The research group is based at the second-largest University Hospital in Germany, providing a collaborative and interdisciplinary environment. Applications are accepted on a rolling basis; interested candidates should contact Prof. Jan-Bernd Hövener at [email protected].