Jussara Amato at University of Naples Federico II - Research Interests, Publications & Academic Profile

Jussara Amato

University of Naples Federico II

Italy

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Research Interests

Biochemistry

30%

Cell Biology

20%

Chemical Biology

30%

Drug Repurposing

20%

Telomere Biology

20%

Huntington's Disease

20%

Molecular Biology

20%

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Recent Grants

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Discovery of new ligands, specifically targeting bile acid receptors, for the treatment of liver and metabolic disorders

Open Date: 2017-01-01

Close Date:

Articles8

Ligand-based drug repurposing strategy identified SARS-CoV-2 RNA G-quadruplex binders.

Article Link

Year:

2022

Combination of dl922-947 Oncolytic Adenovirus and G-Quadruplex Binders Uncovers Improved Antitumor Activity in Breast Cancer

Article Link

Year:

2022

Truncated Analogues of a G-Quadruplex-Forming Aptamer Targeting Mutant Huntingtin: Shorter Is Better!

Article Link

Year:

2022

Fighting the Huntington’s Disease with a G-Quadruplex-Forming Aptamer Specifically Binding to Mutant Huntingtin Protein: Biophysical Characterization, In Vitro and In Vivo Studies

Article Link

Year:

2022

Synthesis and Characterization of Bis-Triazolyl-Pyridine Derivatives as Noncanonical DNA-Interacting Compounds

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Year:

2021

Targeting of Telomeric Repeat-Containing RNA G-Quadruplexes: From Screening to Biophysical and Biological Characterization of a New Hit Compound

Article Link

Year:

2021

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–7

Article Link

Year:

2020

Toward G-Quadruplex-Based Anticancer Agents: Biophysical and Biological Studies of Novel AS1411 Derivatives

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Year:

2020

Collaborators19

George Kokotos

National and Kapodistrian University of Athens

GREECE

Bruno Pagano

Full Professor

University of Naples Federico II

ITALY

Maurizio Pellecchia

Professor

University of California

UNITED STATES

Diego Muñoz-Torrero

Full Professor of Organic & Medicinal Chemistry

University of Barcelona

SPAIN

Gian Cesare Tron

Università degli Studi del Piemonte Orientale

ITALY

Michael Gütschow

University of Bonn

GERMANY

Domenica Capasso

University of Naples Federico II

ITALY

Bruno Catalanotti

Assistant Professor

University of Naples Federico II

ITALY

Daniela Montesarchio

Full Professor

Università degli Studi di Napoli Federico II

ITALY

STEFANO MANGANI

Full Professor of Chemistry

University of Siena

ITALY

Katalin Prokai-Tatrai

Professor

University of North Texas Health Science Center

UNITED STATES

Giuseppe PORTELLA

Professor

Università degli Studi di Napoli Federico II

ITALY

Ivan Kosalec

CROATIA

Mariarosa AB Melone

Professore Associato di Neurologia

Università degli Studi della Campania Luigi Vanvitelli Scuola di Medicina e Chirurgia

ITALY

diego brancaccio

Assistant Professor (RTDb)

University of Naples Federico II

ITALY

Nunzia Iaccarino

Assistant Professor

University of Naples Federico II

ITALY

Yasu-Taka Azuma

JAPAN

Peter Scott

Associate Professor

University of Michigan

UNITED STATES

Jarkko Rautio

Professor in pharmaceutical chemistry

University of Eastern Finland

FINLAND

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