Osvaldo Graña Castro at Universidad CEU San Pablo Facultad de Medicina - Research Interests, Publications & Academic Profile

Osvaldo Graña Castro

Full-time professor

Universidad CEU San Pablo Facultad de Farmacia

Spain

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Research Interests

Cell Biology

100%

Biochemistry

40%

Cancer Biology

50%

Autophagy

30%

Genomic Instability

20%

Insulin Resistance

20%

Cell Division

20%

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Articles15

A mild increase in nutrient signaling to mTORC1 in mice leads to parenchymal damage, myeloid inflammation and shortened lifespan

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Year:

2024

Hepatic nutrient and hormone signaling to mTORC1 instructs the postnatal metabolic zonation of the liver

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Year:

2024

Severe Allergy as a Chronic Inflammatory Condition From a Systems Biology Perspective

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2024

Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis.

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2023

Mammalian CDC14 phosphatases control exit from stemness in pluripotent cells

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2023

Pseudoalignment tools as an efficient alternative to detect repeated transposable elements in scRNAseq data

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Year:

2023

The nucleolar aberrancies that drive ribosome impairment induced by RNA binding proteins are hallmarks of aging

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Year:

2023

Hnrnpk Overexpression Drives Nucleolar Aberrancies Causing Ribosomopathies

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Year:

2023

Luminal Rank loss decreases cell fitness leading to basal cell bipotency in parous mammary glands

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Year:

2023

A clinically compatible drug-screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis

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2022

3D chromatin connectivity underlies replication origin efficiency in mouse embryonic stem cells

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2022

Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3′ untranslated region

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2022

Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism

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Year:

2022

Micrornas targeting HIF-2α, VEGFR1 and/or VEGFR2 as potential predictive biomarkers for VEGFR tyrosine kinase and HIF-2α inhibitors in metastatic clear-cell renal cell carcinoma

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Year:

2021

Micrornas possibly involved in the development of bone metastasis in clear-cell renal cell carcinoma

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Year:

2021

Collaborators14

Javier Munoz

Research Professor

Ikerbasque, Basque Foundation for Science

SPAIN

Rebecca Lee

The University of Manchester

UNITED KINGDOM

Andrada Ianus

Lecturer

King’s College London

UNITED KINGDOM

Neta Erez

ISRAEL

Sandra Rodriguez-Perales

Head of Molecular Cytogenetics & Genome Editing Unit

Centro Nacional de Investigaciones Oncológicas

SPAIN

Gabriel Piedrafita

Universidad Complutense de Madrid

SPAIN

Viviana Loria-Kohen

Profesor Ayudante Doctor

Universidad Complutense de Madrid

SPAIN

Miguel Lafarga

Full Professor (Emeritus)

Universidad de Cantabria

SPAIN

SONIA MARTINEZ GONZALEZ

Head of Medicinal Chemistry

Centro Nacional de Investigaciones Oncológicas

SPAIN

Susana Garcia-Silva

Adjunct Professor of Systems Biology

Universidad Carlos III de Madrid - Campus de Leganés

SPAIN

Ana Losada

Head of Chromosome Dynamics group

SPAIN

Eva Maria Garrido Martin

Profesor Ayudante Doctor Biología Celular

SPAIN

Jose Fernandez Alen

Profesor Asociado

Universidad Complutense de Madrid Facultad de Medicina

SPAIN

Damir Vareslija

Research Lecturer and Principal Investigator

RCSI University of Medicine and Health Sciences

IRELAND

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