Tillie-Louise Hackett at The University of British Columbia - Research Interests, Publications & Academic Profile

Tillie-Louise Hackett

Professor

The University of British Columbia

Canada

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Research Interests

Epidemiology

20%

Cardiology

20%

Inflammatory Biology

50%

Pulmonary Fibrosis

50%

Lung Disease

50%

Respiratory Medicine

40%

Bronchoscopy

30%

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Articles13

Extracellular Matrix Remodeling in Atopic Dermatitis Harnesses the Onset of an Asthmatic Phenotype and Is a Potential Contributor to the Atopic March.

Article Link

Year:

2024

Interleukin-1α inhibits transforming growth factor-β1 and β2-induced extracellular matrix production, remodeling and signaling in human lung fibroblasts: Master regulator in lung mucosal repair

Article Link

Year:

2024

Platelet Activating Factor Receptor and Intercellular Adhesion Molecule–1 Expression Increases in the Small Airway Epithelium and Parenchyma of Patients with Idiopathic Pulmonary Fibrosis: Implications for Microbial Pathogenesis

Article Link

Year:

2024

TGF-β1, pSmad-2/3, Smad-7, and β-Catenin Are Augmented in the Pulmonary Arteries from Patients with Idiopathic Pulmonary Fibrosis (IPF): Role in Driving Endothelial-to-Mesenchymal Transition (EndMT)

Article Link

Year:

2024

Taking Small Airways in Chronic Obstructive Pulmonary Disease to TASC

Article Link

Year:

2023

Hedgehog Signaling as a Therapeutic Target for Airway Remodeling and Inflammation in Allergic Asthma

Article Link

Year:

2022

The Role of the Dynamic Lung Extracellular Matrix Environment on Fibroblast Morphology and Inflammation

Article Link

Year:

2022

Reply to Cottin: Small Airways in Pulmonary Fibrosis: Revisiting an Old Question with New Tools

Article Link

Year:

2022

Angiotensin-Converting Enzyme 2 (ACE2), Transmembrane Peptidase Serine 2 (TMPRSS2), and Furin Expression Increases in the Lungs of Patients with Idiopathic Pulmonary Fibrosis (IPF) and Lymphangioleiomyomatosis (LAM): Implications for SARS-CoV-2 (COVID-19) Infections

Article Link

Year:

2022

Modeling Extracellular Matrix-Cell Interactions in Lung Repair and Chronic Disease

Article Link

Year:

2021

Pulmonary Vascular Remodeling Is an Early Feature of Fatal and Nonfatal Asthma

Article Link

Year:

2021

What Have In Vitro Co-Culture Models Taught Us about the Contribution of Epithelial-Mesenchymal Interactions to Airway Inflammation and Remodeling in Asthma?

Article Link

Year:

2020

Reply to Janssen and Wouters: Loss of Alveolar Attachments as a Pathomechanistic Link between Small Airway Disease and Emphysema

Article Link

Year:

2020

Collaborators7

sathish venkatachalem

North Dakota State University

UNITED STATES

Emmanuel Twumasi Osei

Assistant Professor

University of British Columbia Okanagan

CANADA

Susanne Lau

Senior Consultant, Professor

Charité - Universitätsmedizin Berlin

GERMANY

Sukhwinder Singh Sohal

AUSTRALIA

Leila Mostaço-Guidolin

Assistant Professor

Carleton University

CANADA

Chinten James Lim

Associate Professor

The University of British Columbia

CANADA

Don D. Sin

The University of British Columbia

CANADA

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