Publisher
source

King’s College London

Top university

Immune–Epithelial Interactions King’s College London in United Kingdom

Degree Level

Postdoc

Field of study

Biology

Funding

Fixed-term contract, part-time (20 hours/week) until 1st August 2026. Salary and grade depend on PhD status (Grade 5 for those awaiting PhD award, Grade 6 for PhD holders).

Deadline

Aug 1, 2026

Country flag

Country

United Kingdom

University

King’s College London

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Where to contact

Official Email

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Keywords

Biology
Stem Cell Biology
Flow Cytometry
Health Science
Single-cell Analysis
Immunohistochemistry
Tumor Immunology
Organogenesis
Transgenic Animal Models
Epithelial Biology
Regulatory T Cells
Regeneration Biology
Tissue Repair
Tumor Progression

About this position

The Immune–Epithelial Interactions Laboratory at King’s College London, based at Guy’s Hospital within the Centre for Gene Therapy and Regenerative Medicine, is seeking a part-time Postdoctoral Research Associate. The lab investigates how immune cells, particularly regulatory T cells (Tregs), interact with epithelial and stromal compartments to orchestrate organ development, tissue repair, and tumour progression. This research spans fundamental mechanisms of neonatal organogenesis through to translational insights in regenerative disease and cancer.

The successful candidate will work on a project aiming to uncover how Tregs regulate neonatal lung and skin organogenesis, adult tissue homeostasis, and tumour-associated remodelling. The role involves using in vivo transgenic models, cancer models, multi-parameter flow cytometry, single-cell and bulk RNA sequencing, and advanced immunofluorescence imaging to dissect the molecular and cellular pathways by which Tregs control epithelial stem cell behaviour and tissue regeneration. The post holder will report to Dr Niwa Ali and collaborate with teams across King’s College London and Guy’s and St Thomas’ NHS Foundation Trust.

Applicants must have a PhD in immunology, developmental biology, or a closely related field, with strong experience in experimental mouse models, flow cytometry, and transcriptomic analysis. The position is part-time (20 hours per week) on a fixed-term contract until 1st August 2026, with salary and grade dependent on PhD status. The role requires part-time on-site work and offers at least 10 days per year (pro-rata) for professional development.

The lab and institution are committed to diversity, inclusion, and supporting career development. Occupational Health clearance is required. Candidates should submit a CV and supporting statement addressing the essential and, if possible, desirable criteria.

Funding details

Fixed-term contract, part-time (20 hours/week) until 1st August 2026. Salary and grade depend on PhD status (Grade 5 for those awaiting PhD award, Grade 6 for PhD holders).

What's required

Applicants must hold a PhD in immunology, developmental biology, or a closely related discipline, or have submitted their thesis and be awaiting award of their PhD. Essential experience includes at least two first-author publications in peer-reviewed journals, extensive experience with experimental mouse models of tissue injury, direct experience with mouse cancer models, a valid UK Home Office Personal Licence (modules A, B, and C), expertise in multicolour flow cytometry (≥12 colours), strong skills in tissue processing for histology and immunofluorescence, ability to independently analyse both bulk and single-cell RNA sequencing datasets, direct experience with human blood handling (including PBMC extraction and in vitro co-cultures), and familiarity with advanced imaging and image analysis platforms (e.g., confocal microscopy, 3D imaging, ImageJ or Imaris analysis). Desirable criteria include experience processing mouse lung and/or skin tissue for histology and immunofluorescence, performing in vivo experimentation in mouse lung and/or skin models, and in vitro calcium imaging for cell signalling dynamics. Occupational Health clearance is required.

How to apply

Submit a copy of your CV and a supporting statement detailing how you meet the essential criteria listed in the advert. If shortlisted, desirable criteria may be used for final selection. Refer to the Job Description document for full details and visit the 'How we Recruit' pages for more information.

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