The Molecular Toxicology and Epigenetics (EpiTox) group at Uppsala University, led by Professor Joëlle Rüegg, is recruiting a postdoctoral researcher in bioinformatics and a PhD student in molecular biology. The group investigates the role of epigenetic mechanisms in neurodevelopmental effects of environmental chemicals and the influence of circadian rhythms on epigenetic patterns and toxic responses. Research is conducted within a vibrant, international environment at the Department of Organismal Biology, with strong collaborations including Karlstad University and the University of Cologne.

The postdoctoral position focuses on epigenetic data analysis, particularly bioinformatic and biostatistical analyses of epigenomic datasets generated by Oxford Nanopore sequencing and Illumina EPIC arrays. The project, funded by Formas, aims to identify epigenetic markers for exposure-related health effects in humans, with a special emphasis on neurodevelopment. The postdoc will also conduct literature reviews and meta-analyses, contribute to scientific publications, and participate in group and departmental activities. Applicants must have a recent doctoral degree in bioinformatics, biostatistics, computational biology, or a related field, with strong skills in R or Python, experience in long-read sequencing and DNA methylation data analysis, and excellent English communication abilities.

The PhD position, embedded in a VR-funded project, investigates how DNA methylation patterns are regulated across the circadian cycle. The student will primarily work in the wet lab, performing mammalian cell culture, molecular biology methods, and CRISPR-based tagging, as well as learning bioinformatic analyses of DNA methylation and RNA-seq datasets. Applicants must hold a Master’s degree or equivalent in molecular biology, cell biology, or a related field, with experience in molecular biology methods and proficiency in English. Additional qualifications include experience with mammalian cell culture, CRISPR/Cas9, and bioinformatics.

Both positions are fully funded, with the postdoc offered a 2-year contract (possible 1-year extension) and the PhD a full-time, fixed-salary appointment. Uppsala University provides a supportive, international research environment with comprehensive employment benefits. The application deadline for both positions is January 30, 2026. For more information and to apply, visit the provided links or contact Professor Joëlle Rüegg at [email protected].