Andreas Hougaard Laustsen at Technical University of Denmark - Research Interests, Publications & Academic Profile

Andreas Hougaard Laustsen

Technical University of Denmark

Denmark

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Research Interests

Biochemistry

50%

Immunology

100%

Antibodies

100%

Toxinology

90%

Bioanalytical Chemistry

40%

Biopharmaceutics

30%

Assay Development

30%

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Recent Grants

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Recombinant snakebite antivenom for sub-Saharan Africa

Open Date: 2021-01-01

Close Date: 2025-12-31

Articles20

ExpoSeq: simplified analysis of high-throughput sequencing data from antibody discovery campaigns

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2024

Discovery of broadly‐neutralizing antibodies against brown recluse spider and Gadim scorpion sphingomyelinases using consensus toxins as antigens

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2024

A comparative study of the performance of E. coli and K. phaffii for expressing α-cobratoxin

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2024

Engineering of pH-dependent antigen binding properties for toxin-targeting IgG1 antibodies using light-chain shuffling

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2024

Antibody-dependent enhancement of toxicity of myotoxin II from Bothrops asper

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2024

Cellulose immobilization strategies for paper-based immunoassays

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2024

Fit‐for‐purpose heterodivalent single‐domain antibody for gastrointestinal targeting of toxin B from Clostridium difficile

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2024

Recombinant snake antivenoms get closer to the clinic

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2024

A comparative study of protein structure prediction tools for challenging targets

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2024

In vivo neutralization of coral snake venoms with an oligoclonal nanobody mixture in a murine challenge model

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2024

Assessing developability early in the discovery process for novel biologics

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2023

Characterisation of two snake toxin-targeting human monoclonal immunoglobulin G antibodies expressed in tobacco plants

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2023

Neutralization capacity of recombinant antivenoms based on monoclonal antibodies and nanobodies

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2023

Cross-reactivity trends when selecting scFv antibodies against snake toxins using a phage display-based cross-panning strategy

Article Link

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2023

Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-neurotoxins from snakes

Article Link

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2023

Prototyping of a lateral flow assay based on monoclonal antibodies for detection of Bothrops venoms

Article Link

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2023

Orally delivered single-domain antibodies against gastrointestinal pathogens

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Year:

2023

A single-chain variable fragment selected against a conformational epitope of a recombinantly produced snake toxin using phage display

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2023

An in vitro assay to investigate venom neurotoxin activity on muscle-type nicotinic acetylcholine receptor activation and for the discovery of toxin-inhibitory molecules

Article Link

Year:

2023

In vitro discovery of a human monoclonal antibody that neutralizes lethality of cobra snake venom

Article Link

Year:

2022

Collaborators22

Chiara Francavilla

The University of Manchester

UNITED KINGDOM

Bjørn Gunnar Voldborg

Technical University of Denmark

DENMARK

Anne Ljungars

Technical University of Denmark

DENMARK

Timothy P. Jenkins

Technical University of Denmark

DENMARK

Julian Harrison

ETH Zürich

SWITZERLAND

Line Ledsgaard

Technical University of Denmark

DENMARK

Selma Belfakir

Technical University of Denmark

DENMARK

Nicholas Casewell

Professor of Tropical Disease Biology

Liverpool School of Tropical Medicine

UNITED KINGDOM

Esperanza Rivera-de-Torre

Technical University of Denmark

DENMARK

Victor Greiff

Associate Professor

University of Oslo

NORWAY

Jonas Arnold Jürgensen

Technical University of Denmark

DENMARK

Serge Muyldermans

Professor

Vrije Universiteit Brussel

BELGIUM

Lone Gram

Technical University of Denmark

DENMARK

Jens Preben Morth

Technical University of Denmark

DENMARK

Marcus Petersson

Technical University of Denmark

DENMARK

Jan Terje Andersen

University of Oslo

NORWAY

Lars Ellgaard

Professor

University of Copenhagen

DENMARK

Winnie Edith Svendsen

Technical University of Denmark

DENMARK

Lise Marie Grav

Technical University of Denmark

DENMARK

Aleksander Haack

Technical University of Denmark

DENMARK

Shirin Ahmadi

Technical University of Denmark

DENMARK

Georgina Ross

Chief Technology Officer

DENMARK

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