Zhuo Shang at The University of Western Australia - Research Interests, Publications & Academic Profile

Zhuo Shang

University of Western Australia

Australia

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Research Interests

Biochemistry

100%

Microbiology

30%

Fungal Biology

40%

Chemical Biology

40%

Allosteric Regulation

30%

Metabolic Biology

30%

Glycobiology

30%

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Recent Grants

Grant: Open

Cheeloo Young Scholar Program Start-up Funding

Open Date: 2022-07-01

Close Date: 2027-06-01

Grant: Close

Unearthing Antimicrobial Lasso Peptides from Uncultured Bacteria

Open Date: 2020-06-01

Close Date: 2021-06-01

Articles13

Discovery and heterologous biosynthesis of glycosylated polyketide luteodienoside A reveals unprecedented glucinol-mediated product offloading by a fungal carnitine O-acyltransferase domain

Article Link

Year:

2024

Metabologenomics-Inspired Discovery and Combinatorial Biosynthesis-Based Diversification of Fungal O-Glycosylated Depsides

Article Link

Year:

2024

Discovery and heterologous biosynthesis of glycosylated polyketide luteodienoside A reveals unprecedented glucinol-mediated product offloading by a fungal carnitine O-acyltransferase domain

Article Link

Year:

2024

Refactoring and Heterologous Expression of Class III Lanthipeptide Biosynthetic Gene Clusters Lead to the Discovery of N,N-Dimethylated Lantibiotics from Firmicutes

Article Link

Year:

2023

Structural basis of transcription activation by Rob, a pleiotropic AraC/XylS family regulator

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Year:

2022

Genome mining of Aspergillus hancockii unearths cryptic polyketide hancockinone A featuring a prenylated 6/6/6/5 carbocyclic skeleton

Article Link

Year:

2021

The genome of Micrococcus luteus MST-118984C isolated from Australian soil harbours a bacteriocin biosynthetic gene cluster and biocide/multidrug efflux genes

Article Link

Year:

2021

Grincamycins P–T: Rearranged Angucyclines from the Marine Sediment-Derived Streptomyces sp. CNZ-748 Inhibit Cell Lines of the Rare Cancer Pseudomyxoma Peritonei

Article Link

Year:

2021

A unique binding between SspA and RNAP β’NTH across low-GC Gram-negative bacteria facilitates SspA-mediated transcription regulation

Article Link

Year:

2021

Bufadienolides from the Eggs of the Toad Bufo bufo gargarizans and Their Antimelanoma Activities

Article Link

Year:

2021

Biochemical and structural analyses reveal critical residues in δ subunit affecting its bindings to β′ subunit of Staphylococcus aureus RNA polymerase

Article Link

Year:

2021

Structural and Functional Analyses of the Transcription Repressor DgoR From Escherichia coli Reveal a Divalent Metal-Containing D-Galactonate Binding Pocket

Article Link

Year:

2020

Total Synthesis of Malacidin A by β‐Hydroxyaspartic Acid Ligation‐Mediated Cyclization and Absolute Structure Establishment

Article Link

Year:

2020

Collaborators8

Alexander Chase

Assistant Professor

Southern Methodist University

UNITED STATES

John Kalaitzis

Macquarie University

AUSTRALIA

Gavin Flematti

University of Western Australia

AUSTRALIA

Hang Li

University of Western Australia

AUSTRALIA

Thomas James Booth

University of Western Australia

AUSTRALIA

Yit-Heng Chooi

University of Western Australia

AUSTRALIA

Andrew Piggott

Macquarie University

AUSTRALIA

Jie Li

University of South Carolina

UNITED STATES

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