Simulation-based assessment of implantation parameters affecting bone–implant stability (PhD Position)

This fully funded PhD position at KU Leuven focuses on simulation-based assessment of implantation parameters affecting bone–implant stability, as part of the Marie Skłodowska-Curie Actions (MSCA) Doctoral Network 'CUSTOM'. The successful candidate will join the Smart Instrumentation team within the division of Biomechanical Engineering, Department of Mechanical Engineering, under the supervision of Prof. Kathleen Denis and Prof. Harry van Lenthe. The research group is dedicated to developing advanced surgical instruments and assistive technologies for medical applications, integrating novel sensing and modelling techniques to improve complex procedures in variable environments such as the human body. The CUSTOM project unites design, manufacturing, and testing disciplines to develop next-generation patient-specific shoulder implants. With shoulder replacements expected to rise dramatically, and a significant failure rate in current implants, the project aims to address major failure mechanisms and improve implant longevity. This PhD project is centered on computational tools for patient-specific design of additively manufactured (porous) shoulder implants, considering both anatomical geometry and local bone quality. Research activities will include determining local bone stiffness using Photon Counting Computed Tomography, creating high-resolution finite element (FE) models of the humerus and glenoid, comparing these with continuum FE models, investigating the impact of various implantation parameters on implant mechanics, and validating results with additively manufactured implants. The project aims to deliver predictive models for pre-surgical planning, enhancing the safety and effectiveness of shoulder implant procedures. The position offers two three-month research stays at leading institutions: validation of personalized shoulder implant results at the University of Birmingham (UK) and further validation with in-situ micro-CT and DIC at TU Delft (NL). The doctoral scholarship is fully funded, starting with one year and extendable up to four years, with a tax-free living allowance of approximately 3,055.61 EUR/month for single candidates, plus mobility and family/leave/special needs allowances. Travel and accommodation for research stays are covered. The successful candidate will be enrolled in the Arenberg Doctoral School, receiving specialized training in an international environment and benefiting from extensive networking and collaboration opportunities within the CUSTOM MSCA network. Applicants must hold a Master's degree in Mechanical, Electromechanical, or Biomedical Engineering (or closely related field) with excellent grades, and have experience in numerical modelling, finite element analysis, and experimental work. Familiarity with biomechanics is advantageous. Excellent English communication skills, independence, and teamwork are essential. MSCA eligibility rules apply: candidates must not have resided or carried out their main activity in Belgium for more than 12 months in the 36 months prior to recruitment, and must not have previously obtained a PhD. KU Leuven offers a vibrant, international research environment in the heart of Europe, with high quality of life and ample opportunities for social and sporting activities. The university is committed to diversity, inclusion, and equal opportunity. For further information, contact Prof. Kathleen Denis at [email protected]. Apply online via the KU Leuven job portal before the deadline of February 12, 2026.