Tomasz Plech at Medical University of Lublin - Research Interests, Publications & Academic Profile

Tomasz Plech

Medical University of Lublin

Poland

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Research Interests

Pharmaceutical Chemistry

100%

Pharmacology

70%

Heterocyclic Chemistry

50%

Natural Products Chemistry

40%

Drug Formulation

40%

Molecular Docking

30%

Chemical Biology

30%

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Recent Grants

Grant: Close

Badania nad przeciwbakteryjną aktywnością i mechanizmem działania nowych pochodnych cyprofloksacyny

Open Date: 2015-03-16

Close Date: 2017-11-15

Grant: Close

Badania nad przeciwdrgawkową aktywnością 4-alkilo-5-arylowych pochodnych 1,2,4-triazolo-3-tionu

Open Date: 2014-08-13

Close Date: 2018-10-12

Grant: Close

Molekularne podstawy aktywności przeciwbakteryjnej w grupie pochodnych tiosemikarbazydu

Open Date: 2013-02-04

Close Date: 2017-08-03

Grant: Close

Synteza pochodnych hydrazydu kwasu 3-chlorobenzoesowego o aktywności przeciwdrobnoustrojowej i przeciwpadaczkowej

Open Date: 2011-05-24

Close Date: 2012-05-23

Articles18

In Vitro and In Silico of Cholinesterases Inhibition and In Vitro and In Vivo Anti-Melanoma Activity Investigations of Extracts Obtained from Selected Berberis Species

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2024

Electrospun Nanofibers with Pomegranate Peel Extract as a New Concept for Treating Oral Infections

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2024

Electrospun Nanofibers Loaded with Marigold Extract Based on PVP/HPβCD and PCL/PVP Scaffolds for Wound Healing Applications

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2024

Elderberry Leaves with Antioxidant and Anti-Inflammatory Properties as a Valuable Plant Material for Wound Healing

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2024

3D-Printed Chitosan-Based Scaffolds with Scutellariae baicalensis Extract for Dental Applications

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2024

Effect of Linker Elongation on the VGSC Affinity and Anticonvulsant Activity among 4-Alkyl-5-aryl-1,2,4-triazole-3-thione Derivatives

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Year:

2023

TZD-Based Hybrid Molecules Act as Dual Anti-Mycobacterium tuberculosis and Anti-Toxoplasma gondii Agents

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Year:

2023

Determination of Some Isoquinoline Alkaloids in Extracts Obtained from Selected Plants of the Ranunculaceae, Papaveraceae and Fumarioideae Families by Liquid Chromatography and In Vitro and In Vivo Investigations of Their Cytotoxic Activity

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Year:

2023

Determination of Selected Isoquinoline Alkaloids from Chelidonium majus, Mahonia aquifolium and Sanguinaria canadensis Extracts by Liquid Chromatography and Their In Vitro and In Vivo Cytotoxic Activity against Human Cancer Cells

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Year:

2023

Identification of the first-in-class dual inhibitors of human DNA topoisomerase IIα and indoleamine-2,3-dioxygenase 1 (IDO 1) with strong anticancer properties

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2023

Thiosemicarbazide Derivatives Targeting Human TopoIIα and IDO-1 as Small-Molecule Drug Candidates for Breast Cancer Treatment

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2023

Combined In Silico and In Vitro Analyses to Assess the Anticancer Potential of Thiazolidinedione–Thiosemicarbazone Hybrid Molecules

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2023

Copper(II) Complexes with 1-(Isoquinolin-3-yl)heteroalkyl-2-ones: Synthesis, Structure and Evaluation of Anticancer, Antimicrobial and Antioxidant Potential

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2023

Chitosan-Based Hydrogels for Controlled Delivery of Asiaticoside-Rich Centella asiatica Extracts with Wound Healing Potential

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2023

Inhibition of Toxoplasma gondii by 1,2,4-triazole-based compounds: marked improvement in selectivity relative to the standard therapy pyrimethamine and sulfadiazine

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2022

Design, Synthesis, and Characterization of Novel Coordination Compounds of Benzimidazole Derivatives with Cadmium

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2022

Zinc Coordination Compounds with Benzimidazole Derivatives: Synthesis, Structure, Antimicrobial Activity and Potential Anticancer Application

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Year:

2022

In Vitro Evaluation of the Antioxidant Activity and Chemopreventive Potential in Human Breast Cancer Cell Lines of the Standardized Extract Obtained from the Aerial Parts of Zigzag Clover (Trifolium medium L.)

Article Link

Year:

2022

Collaborators24

Jarogniew Luszczki

professor

Medical University of Lublin

POLAND

Barbara Kaproń

Medical University of Lublin

POLAND

Adrian Bekier

Assistant Professor

Medical University of Lodz

POLAND

Marcin Świątkowski

Assistant Professor

Lodz University of Technology

POLAND

Anna Petruczynik

Medical University of Lublin

POLAND

Agata Paneth

Medical University of Lublin

POLAND

Judyta Cielecka-Piontek

Poznan University of Medical Sciences

POLAND

Justyna Misiurek

Medical University of Lublin

POLAND

Kinga Paruch

Medical University of Lublin

POLAND

Bogusław Buszewski

Nicolaus Copernicus University

POLAND

Malgorzata Iwona Szynkowska-Jozwik

Prof.

POLAND

Anna Makuch-Kocka

Assistant Professor

Medical University of Lublin

POLAND

Małgorzata Szczesio

Lodz University of Technology

POLAND

Roman Paduch

Medical University of Lublin

POLAND

Wojciech Plazinski

Medical University of Lublin

POLAND

Piotr Paneth

Professor

Lodz University of Technology

POLAND

Małgorzata Szultka-Młyńska

Nicolaus Copernicus University

POLAND

Anita Kornicka

Medical University of Gdansk

POLAND

Nazar Trotsko

Medical University of Lublin

POLAND

Katarzyna Dzitko

Deputy Dean of the Faculty of Biology and Environmental Protection / PhD, DSc, Assoc. Prof. (ENG) dr hab. prof. nadzw. UŁ (PL) / Director of the BioMedChem Doctoral School of the UL and Lodz Institutes of the Polish Academy of Science

University of Łódź

POLAND

Izabela Korona-Glowniak

associate professor/Ph.D.

Medical University of Lublin

POLAND

Magdalena Maciejewska-Turska

Medical University of Lublin

POLAND

Tomasz Karpinski

Poznan University of Medical Sciences

POLAND

TOMASZ TUZIMSKI

Prof. Dr. hab.

Medical University of Lublin

POLAND

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