Defining the Origin of Multilocus Imprinting Disturbance (MLID) – PhD Studentship Aston University in United Kingdom

This PhD studentship at Aston University investigates the origins of multilocus imprinting disturbance (MLID), a condition associated with congenital imprinting disorders and assisted reproductive technologies (ART). The project aims to unravel the genetic and environmental interactions underlying MLID by characterising DNA methylation profiles and identifying candidate germline variants in epigenetic regulator genes among affected individuals. The research is situated within the College of Health and Life Sciences and will be based at the Aston Campus in Birmingham, UK.

Applicants will join a dynamic research environment focused on genetics, epigenetics, and biomedical sciences. The project is supervised by Professor Eamonn Maher, a leading expert in the field. The successful candidate will have access to state-of-the-art facilities and will be expected to engage regularly with the campus community.

Funding covers Home tuition fees; international applicants are welcome but must pay the difference between Home and Overseas tuition fees (£17,712 for 2026/7). Applicants should hold, or expect to obtain, a First or Upper Second Class undergraduate degree (or equivalent) in a relevant subject, or a Merit in a relevant Masters degree plus an undergraduate degree. Overseas qualifications will be assessed for equivalence. English language proficiency is required, with evidence to be provided during the application process if not already met.

To apply, candidates must submit a complete application including transcripts, certificates, a research statement, personal statement, CV, two academic references, evidence of English language proficiency, and a copy of their passport. Incomplete applications will not be considered. Interviews for shortlisted candidates will be conducted online via Microsoft Teams. For further information, applicants may contact Professor Eamonn Maher at [email protected] or the Postgraduate Admissions team at [email protected].

References for the project include recent publications in leading journals, highlighting the cutting-edge nature of the research. This opportunity is ideal for candidates interested in genetics, epigenetics, and the molecular basis of human disease.