Publisher
source

Matthias Barz

4 months ago

PhD Candidate in the Development of Anticancer Nanomedicines Leiden University in Netherlands

Degree Level

PhD

Field of study

Chemistry

Funding

Available

Deadline

Expired

Country flag

Country

Netherlands

University

Leiden University

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Where to contact

Official Email

[email protected]

Keywords

Chemistry
Biomedical Engineering
Materials Science
Drug Delivery
Nanotechnology
Biology
Peptide Chemistry
Antibodies
Health Science
Metabolic Syndrome
Polymer Chemistry
Chemical Synthesis
Nanomedicine
Cancer Therapy
Hospital Pharmacy
Bioconjugation
Polymerization
Therapeutic

About this position

Leiden University’s Faculty of Science and the Leiden Academic Centre for Drug Research (LACDR) invite applications for a PhD position focused on the development of anticancer nanomedicines. This project is part of the NanoMed NL consortium, which brings together Dutch academic and industry partners to advance nanomedicine research and its societal impact. The successful candidate will work in the Barz lab, developing polypept(o)ide-based nanomedicines to enhance current cancer therapies.

The research involves synthesizing functional amino acids, performing solid phase peptide synthesis, and utilizing NCA/NNCA polymerization to create precision polymers. These polymers will be used to construct functional nanomedicines, with anticancer drugs covalently attached via disease-responsive bonds. The efficacy of these systems will be evaluated and compared to conventional antibody drug conjugates (ADCs) within the consortium.

The position offers a stimulating, international research environment in the heart of the Bio Science Park, with access to advanced training and career development opportunities. The appointment is for four years, with a competitive salary and benefits package, including holiday and end-of-year bonuses, and support for international candidates. Applicants should have a Master’s degree in organic chemistry, (bio)pharmacy, or polymer science, with strong synthetic chemistry skills and experience in peptide synthesis or NCA polymerization.

The application process includes submission of a cover letter, CV, transcripts, and reference letters, with interviews and a writing assessment for shortlisted candidates. The deadline for applications is 15 November 2025.

Funding details

Available

What's required

Applicants must hold a Master of Science or equivalent qualification in organic chemistry, (bio)pharmacy, or polymer science. A strong background in synthetic chemistry is required, ideally with experience in peptide synthesis, NCA polymerization, or synthetic organic chemistry. Knowledge of solid phase peptide synthesis and NCA polymerization is preferred, along with a basic understanding of nanoparticle characterization techniques. Candidates should be able to work in an interdisciplinary team, be highly self-motivated, goal-oriented, and demonstrate initiative, persistence, and accountability. Application documents required include a cover letter, CV, transcripts of bachelor and master courses with grades, and preferably two reference letters. An assessment of writing skills is part of the application process.

How to apply

Submit your application online via the provided link. Upload a cover letter, CV, transcripts of bachelor and master courses (including grades), and preferably two reference letters in PDF format. Applications must be received before 15 November 2025. Candidates will be invited for an interview and a writing skills assessment.

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