This postdoctoral scientist position at Julius-Maximilians-Universität Würzburg offers an exciting opportunity to join the laboratory of Professor Jörg Vogel and contribute to cutting-edge research in programmable RNA antibiotics using antisense oligonucleotide (ASO) technology. The research focuses on developing and applying programmable RNA antibiotics for diverse microbes and bacteriophages, with the aim of addressing the global challenge of antimicrobial resistance. ASO technology enables the rational design of antimicrobials that can specifically target and modulate bacterial gene expression, suppressing mRNA translation of essential proteins and providing new solutions for combating emerging pathogens, drug-resistant strains, and undesired activities of commensals, while sparing the native microbiome.

The Vogel lab offers multiple projects that extend beyond pathogen eradication, including interference with commensal activities and targeting bacteriophages in the context of phage therapy. The research group is internationally recognized, with recent publications in Nature, RNA, and Nucleic Acids Research. More information about ongoing research can be found at the Helmholtz Institute for RNA-based Infection Research website.

Applicants should possess a doctoral or PhD degree in molecular biology, biotechnology, chemistry, genomics, computational science, or pharmaceutical science. The position is available full- or part-time, initially for two years with the possibility of extension. Salary is based on the German public sector pay scale (TV-L) and will be commensurate with qualifications. The university encourages applications from qualified women and gives preference to handicapped persons in case of equal aptitude.

To apply, candidates should email a single PDF file containing a short letter of motivation, CV, publication list, copies of relevant documents and certificates, and contact information for two academic references, with the reference 'ASO' to Monika Schraut ([email protected]) by January 11th, 2026. For further information about available projects, applicants may contact Prof. Jörg Vogel at [email protected]. Please note that application documents will not be returned unless a stamped envelope is provided.

This position is ideal for researchers interested in molecular mechanisms of infection, antimicrobial drug development, and innovative RNA-based technologies. The successful candidate will join a vibrant research environment in Würzburg, Germany, and contribute to impactful solutions in the fight against antimicrobial resistance.