David Goldstone at The University of Auckland - Research Interests, Publications & Academic Profile

David Goldstone

Associate Professor

University of Auckland

New Zealand

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Research Interests

Biochemistry

40%

Organic Chemistry

40%

Heterocyclic Chemistry

40%

Molecular Biology

40%

Protein Chemistry

30%

Coordination Chemistry

30%

Supramolecular Chemistry

30%

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Recent Grants

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Trimming retroviral infection: Structural investigations of TRIM protein function

Open Date: 2012-01-01

Close Date: 2017-01-01

Articles12

Not All Binding Sites Are Equal: Site Determination and Folding State Analysis of Gas‐Phase Protein‐Metallodrug Adducts

Article Link

Year:

2024

Platinum(terpyridine) complexes with N-heterocyclic carbene co-ligands: high antiproliferative activity and low toxicity in vivo

Article Link

Year:

2023

The Leptospermum scoparium (Mānuka)-Specific Nectar and Honey Compound 3,6,7-Trimethyllumazine (LepteridineTM) That Inhibits Matrix Metalloproteinase 9 (MMP-9) Activity

Article Link

Year:

2023

Mapping the interaction between Trim28 and the KRAB domain at the center of Trim28 silencing of endogenous retroviruses

Article Link

Year:

2022

Probing the Paradigm of Promiscuity for N-Heterocyclic Carbene Complexes and their Protein Adduct Formation.

Article Link

Year:

2021

Anthracenyl Functionalization of Half-Sandwich Carbene Complexes: In Vitro Anticancer Activity and Reactions with Biomolecules

Article Link

Year:

2021

Probing the Paradigm of Promiscuity for N‐Heterocyclic Carbene Complexes and their Protein Adduct Formation

Article Link

Year:

2021

Structural Analysis of the Menangle Virus P Protein Reveals a Soft Boundary between Ordered and Disordered Regions

Article Link

Year:

2021

Mustards-Derived Terpyridine–Platinum Complexes as Anticancer Agents: DNA Alkylation vs Coordination

Article Link

Year:

2021

Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix

Article Link

Year:

2021

A Combined Spectroscopic and Protein Crystallography Study Reveals Protein Interactions of RhI(NHC) Complexes at the Molecular Level

Article Link

Year:

2020

The RING domain of TRIM69 promotes higher-order assembly

Article Link

Year:

2020

Collaborators8

Matthew Sullivan

University of Auckland

NEW ZEALAND

Margaret Brimble

Distinguished Professor

University of Auckland

NEW ZEALAND

Davide Mercadante

Senior Lecturer

University of Auckland

NEW ZEALAND

Kerry M. Loomes

University of Auckland

NEW ZEALAND

Monika Cziferszky

University of Innsbruck

AUSTRIA

isabelle lucet

Division Head

Walter and Eliza Hall Institute of Medical Research

AUSTRALIA

Muhammad Hanif

University of Auckland

NEW ZEALAND

Christian Hartinger

University of Auckland

NEW ZEALAND

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