Dik C. van Gent

Erasmus University Rotterdam

Netherlands

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Research Interests

Cell Biology

50%

Biochemistry

50%

Cancer Biology

60%

Diagnostic Assay

30%

In Vivo Testing

30%

Tissue Biology

20%

Dna Damage

20%

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Articles14

Development of an Ex Vivo Functional Assay for Prediction of Irradiation Related Toxicity in Healthy Oral Mucosa Tissue

Article Link

Year:

2024

Ex vivo radiation sensitivity assessment for individual head and neck cancer patients using deep learning-based automated nuclei and DNA damage foci detection

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Year:

2024

Functional Homologous Recombination (HR) Screening Shows the Majority of <i>BRCA1/2</i>-Mutant Breast and Ovarian Cancer Cell Lines Are HR-Proficient

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Year:

2024

Establishing a Microfluidic Tumor Slice Culture Platform to Study Drug Response

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Year:

2023

Ex Vivo Functional Assay for Evaluating Treatment Response in Tumor Tissue of Head and Neck Squamous Cell Carcinoma

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Year:

2023

Proof-of-concept study linking ex vivo sensitivity testing to neoadjuvant anthracycline-based chemotherapy response in breast cancer patients

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Year:

2023

A Microfluidic Cancer-on-Chip Platform Predicts Drug Response Using Organotypic Tumor Slice Culture

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Year:

2022

Rapid recruitment of p53 to DNA damage sites directs DNA repair choice and integrity

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Year:

2022

Preclinical Assessment of the Combination of PSMA-Targeting Radionuclide Therapy with PARP Inhibitors for Prostate Cancer Treatment

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Year:

2022

Functional RECAP (REpair CAPacity) assay identifies homologous recombination deficiency undetected by DNA-based BRCAness tests

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Year:

2022

The COMPLETE trial

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Year:

2022

Functional Ex Vivo Tissue-Based Chemotherapy Sensitivity Testing for Breast Cancer

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Year:

2022

Biallelic variants in LIG3 cause a novel mitochondrial neurogastrointestinal encephalomyopathy

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Year:

2021

A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair

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Year:

2021

Collaborators9

Nienke D. Sijtsema

Erasmus University Rotterdam

NETHERLANDS

Wai Leong Tam

Associate Professor (Adjunct)

National University Singapore Yong Loo Lin School of Medicine

SINGAPORE

NITIKA TANEJA

Associate Professor

Erasmus MC

NETHERLANDS

Yu-Hsiu Wang

Research Assistant Professor

University of Texas Medical Branch

UNITED STATES

Wilma Heemsbergen

Erasmus University Rotterdam

NETHERLANDS

jose angelito hardillo

Head and neck surgeon

Erasmus University Medical Center

NETHERLANDS

Wytske M. van Weerden

Erasmus University Medical Center

NETHERLANDS

Elena Bonora

Associate Professor

University of Bologna

ITALY

Brita Singers Sørensen

Aarhus University

DENMARK

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