PhD Position in Confidential High Performance Computing for AI in Cancer Care
The University of Basel’s High Performance Computing (HPC) research group, led by Professor Florina M. Ciorba in the Department of Mathematics and Computer Science, is offering a fully funded PhD position as part of the SNF Bridge Discovery project “Family Gene Toolkit: A digital service to support genetic care in Europe.” This interdisciplinary project brings together experts in HPC, nursing, social sciences, and 14 clinical partners across Switzerland to advance the Family Gene Toolkit (FGT), a digital platform supporting families affected by Hereditary Breast and Ovarian Cancer (HBOC) and Lynch Syndrome (LS).
The next phase, FGT v3.0, will integrate cutting-edge AI and confidential computing to personalize patient care and improve clinical outcomes. As a PhD candidate, you will be responsible for building the secure technical foundation for FGT 3.0, including confidential HPC pipelines, scalable training infrastructure, and fine-tuned medical large language models (LLMs) trained on clinical guidelines, evidence-based datasets, and real-world medical corpora. You will rigorously evaluate these models using established medical and multilingual benchmarks and contribute to the development of prototype chatbot and retrieval systems for clinical partners.
Your research will focus on designing, developing, and integrating AI-based and privacy-preserving features into FGT v3.0 within a confidential HPC environment. Key tasks include training and fine-tuning large medical LLMs (up to 70B parameters) on confidential HPC systems, preparing medical datasets (Clinical Guidelines, NCCN, PubMed, MIMIC) for secure LLM training, developing high-performance pipelines for TEE-based model training and inference, benchmarking models, and integrating medical LLMs with multilingual models (Apertus). You will also contribute to robustness and confidential-AI evaluation workflows.
Additional responsibilities include conducting research aligned with project objectives, writing and submitting high-quality papers to leading conferences and journals in HPC and AI for healthcare, presenting results at seminars, workshops, and international conferences, and actively collaborating within the HPC group and across partner institutions. You will assist with teaching (one class per semester) and supervision (one or more students per semester).
Eligibility requirements include a Master’s degree in Computer Science, Engineering, or a closely related field by March 2026, an excellent academic record, programming skills in C, C++, Java, or Python, experience with parallel programming, Linux, machine-learning frameworks, and privacy-enhancing technologies, fluency in English, and strong communication and problem-solving skills. A genuine curiosity for Computer Science and motivation to conduct impactful research in healthcare are essential.
The position offers 100% funding per SNSF guidelines (currently approx. CHF 50,000 gross/year), generous travel funds for international conferences, access to powerful supercomputers, close research mentoring, and excellent working conditions in a stimulating and supportive environment. The start date is April 2026, and the position duration is four years.
To apply, submit a single PDF file containing your CV (with publication list), Bachelor’s and Master’s theses, at least one relevant publication (if available), transcripts, links to personal software contributions, a motivation statement, and contact information for 1-2 professors willing to provide recommendation letters. Applications are encouraged before 18 January 2026. Evaluation begins 19 January 2026 and continues until the position is filled. For specific questions, contact Prof. Florina M. Ciorba at [email protected].
Application link:
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