Postdoctoral Positions: Mechanisms of the Zygotene Cilium in Oocyte Development (Elkouby Lab, Hebrew University of Jerusalem)

The Elkouby Lab at The Hebrew University of Jerusalem is offering two postdoctoral positions to investigate the principles and mechanisms of the zygotene cilium, a newly identified cilium in developing oocytes. Located at the Ein Kerem campus, the lab is part of the Department of Developmental Biology and Cancer Research, which is renowned for its interdisciplinary approach to cellular growth, differentiation, and morphogenesis. The research focuses on early oogenesis, from germline stem cells to primary follicles, and is funded by the European Research Council (ERC). This project centers on the zygotene cilium, a previously unrecognized structure essential for meiotic chromosomal pairing and germ cell morphogenesis. The Elkouby Lab has established its role in both zebrafish and mouse models, demonstrating its importance in ovary development and fertility. The successful candidates will explore ciliary mechanics, developmental signaling, and reproductive biology using advanced live imaging, genetic manipulation, and deep-learning image analysis. The research also aims to translate findings to the understanding of human ciliopathic proteins. Postdoctoral researchers will join an international team and participate in a collaborative effort to decipher the mechanical, functional, and regulatory components of the zygotene cilium. Responsibilities include advanced imaging, genetic manipulation in zebrafish, molecular analyses, and opportunities to engage in single-cell transcriptomics, proteomics, and developmental modeling. The lab provides access to state-of-the-art microscopy and a long-term ovary culture system for live imaging. Applicants should hold a PhD in life sciences, with a strong background in developmental biology and expertise in zebrafish research, genetics, and transgenesis. Excellent communication skills in English are required. Additional skills in molecular biology, microscopy, imaging, single-cell transcriptomics, or proteomics are advantageous. The annual fellowship ranges from $38,000 to $42,000 (NIS equivalent), funded by the ERC. The Hebrew University of Jerusalem is a globally recognized research institution, fostering diversity, equity, and inclusion. The Ein Kerem campus is a central hub for medical and health-related research, offering a vibrant academic and cultural environment in Jerusalem. The university welcomes applicants from all backgrounds and encourages international collaboration. To apply, submit a letter of motivation, CV (including publications), and a copy of your academic degree(s) as three separate PDF files via the application portal before the deadline of December 16, 2025.