Uppsala University’s Molecular Toxicology and Epigenetics (EpiTox) group is recruiting for both a PhD studentship in circadian epigenomics and a postdoctoral position in epigenomic data analysis. The research focuses on understanding how DNA methylation patterns are regulated across the circadian cycle and the role of epigenetic mechanisms in neurodevelopmental effects of environmental chemicals. The EpiTox group is part of the Department of Organismal Biology and the Physiology and Environmental Toxicology research program, providing a vibrant, international, and interdisciplinary environment.

The PhD project, funded by the Swedish Research Council (VR), investigates circadian regulation of DNA methylation and its implications for neurodevelopment. The successful candidate will work primarily in the wet lab, performing mammalian cell culture, DNA/RNA extraction, CRISPR-based tagging, and bioinformatic analyses (DNA methylation and RNA-seq) using R or Python. The project includes collaboration with Dr. Philipp Antczak (University of Cologne) for bioinformatics. Applicants must have a Master’s degree in molecular biology, cell biology, or a related field, experience with molecular biology methods, and strong English skills. Additional experience with cell culture, CRISPR, and bioinformatics is advantageous.

The postdoctoral position, funded by the Formas EpiDNT project, focuses on bioinformatic and biostatistical analysis of epigenomic datasets from both cellular models and human samples, including Oxford Nanopore and Illumina EPIC data. The postdoc will also conduct literature reviews and meta-analyses to identify epigenomic markers of chemically induced neurodevelopmental effects. Collaboration with Professor Carl-Gustaf Bornehag (Karlstad University) is included. Applicants must have a PhD in bioinformatics, biostatistics, computational biology, or a similar field, with experience in R or Python, long-read sequencing, DNA methylation data analysis, and environmental epigenomics. Excellent English communication skills and the ability to work independently and collaboratively are required.

Both positions are fully funded, full-time, and offer competitive salaries and benefits. The PhD position is a temporary appointment as per Swedish Higher Education Ordinance, and the postdoc is a 2-year contract with a possible 1-year extension. The application deadline for both positions is January 30, 2026. Uppsala University is committed to providing a supportive and inclusive work environment for its 7,600 employees and 53,000 students.

For more information and to apply, visit the provided application links. For specific questions, contact Professor Joëlle Rüegg at [email protected].