Tiziano Tuccinardi at Università degli Studi di Pisa - Research Interests, Publications & Academic Profile

Tiziano Tuccinardi

Full Professor

University of Pisa

Italy

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Research Interests

Biochemistry

40%

Pharmacology

90%

Chemical Biology

70%

Molecular Modeling

30%

Neuroprotection

20%

Computational Biology

20%

Virtual Screening

20%

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Articles18

The Benzoylpiperidine Fragment as a Privileged Structure in Medicinal Chemistry: A Comprehensive Review

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Year:

2024

SMS121, a new inhibitor of CD36, impairs fatty acid uptake and viability of acute myeloid leukemia

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Year:

2024

An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent

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Year:

2024

A comprehensive review of synthetic strategies and SAR studies for the discovery of PfDHODH inhibitors as antimalarial agents. Part 1: triazolopyrimidine, isoxazolopyrimidine and pyrrole-based (DSM) compounds

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Year:

2024

Chemical composition, fatty acid profile, antioxidant content, and microbiological loads of lesser mealworm, mealworm, and superworm larvae

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Year:

2024

Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors

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Year:

2024

An in silico toolbox for the prediction of the potential pathogenic effects of missense mutations in the dimeric region of hRPE65

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Year:

2023

VenomPred 2.0: A Novel In Silico Platform for an Extended and Human Interpretable Toxicological Profiling of Small Molecules

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Year:

2023

MolBook UNIPI─Create, Manage, Analyze, and Share Your Chemical Data for Free

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Year:

2023

Identification of New GSK3β Inhibitors through a Consensus Machine Learning-Based Virtual Screening

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Year:

2023

A Multitarget Approach against Neuroinflammation: Alkyl Substituted Coumarins as Inhibitors of Enzymes Involved in Neurodegeneration

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Year:

2023

Dissecting the Activity of Catechins as Incomplete Aldose Reductase Differential Inhibitors through Kinetic and Computational Approaches

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Year:

2022

Machine Learning-Based Virtual Screening for the Identification of Cdk5 Inhibitors

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Year:

2022

Predicting potentially pathogenic effects of hRPE65 missense mutations: a computational strategy based on molecular dynamics simulations

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Year:

2022

Sirtuin 1-Activating Compounds: Discovery of a Class of Thiazole-Based Derivatives

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Year:

2022

Growth performances, chemical composition, and microbiological loads of mealworm reared with brewery spent grains and bread leftovers

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Year:

2022

Resveratrol Analogues as Dual Inhibitors of Monoamine Oxidase B and Carbonic Anhydrase VII: A New Multi-Target Combination for Neurodegenerative Diseases?

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Year:

2022

miRNA-203b-3p Induces Acute and Chronic Pruritus through 5-HTR2B and TRPV4.

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Year:

2022

Collaborators18

Roberta Moschini

University of Pisa

ITALY

Filippo Minutolo

Full Professor of Medicinal Chemistry

University of Pisa

ITALY

Filippo Fratini

Università degli studi di Pisa Dipartimento di Scienze Veterinarie

ITALY

Francesco De Logu

University of Florence

ITALY

Simone Mancini

University of Pisa

ITALY

Stefano Ricagno

Full Professor

University of Milan

ITALY

Karin Lindkvist

Professor in Cell biology

Lund University

SWEDEN

ANTONELLA DEL CORSO

University of Pisa

ITALY

MARIO CAPPIELLO

Associate Professor

University of Pisa

ITALY

Gian Carlo Demontis

Professor

University of Pisa

ITALY

Carlotta Granchi

University of Pisa

ITALY

Mariangela Agamennone

Associate professor

University of Chieti-Pescara

ITALY

Alma Martelli

University of Pisa

ITALY

Alessandro Saba

University Hospital of Pisa

ITALY

Alessandra Ammazzalorso

ITALY

Roberto Amerigo Papini

University of Pisa

ITALY

Flavio Rizzolio

Full Professor

Ca' Foscari University of Venice

ITALY

Lara Testai

University of Pisa

ITALY

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