[4-year Norwich Research Park Biosciences Doctoral Training Partnership PhD CASE studentship with Inspiralis Limited. Includes payment of tuition fees, £20,780 stipend per year, and a Research Training Support Grant of £5,000 per year.] This fully funded PhD studentship at the University of East Anglia, in partnership with the Norwich Research Park Biosciences Doctoral Training Programme (NRPDTP), investigates the influence of placenta partially methylated domains (PMDs) on global epigenetic profiles. The project is supervised by Professor David Monk (University of East Anglia) and Dr. Wilfried Haerty (Earlham Institute), offering a collaborative research environment with access to world-leading expertise in placental biology and epigenomics. The research aims to understand how PMDs affect gene transcription, enhancer selection, and epigenetic responsiveness to developmental cues. The successful candidate will employ advanced molecular biology techniques, including RNA-seq, methyl-seq, CUT&Tag, and hiC, to generate comprehensive expression, histone, and methylation profiles, as well as chromatin contact maps in placental tissue. Bioinformatic analysis will be a key component, helping to elucidate the functional role of PMDs in both health and disease contexts. The studentship provides a stipend of £20,780 per year, full payment of tuition fees, and a Research Training Support Grant of £5,000 annually for four years. The programme also includes a three-month professional internship placement (PIPS) to enhance career development. Applicants should hold at least a UK equivalent Bachelors (Honours) degree with a minimum 2:1 classification, and a Master's degree is preferred. English language proficiency is required (IELTS 6.5 overall, 6 in each category). The position is full-time, starting 1 October 2026, with interviews scheduled for early February 2026. Prospective students are strongly encouraged to contact the supervisors to discuss the project before submitting a formal application. For further details and to apply, visit the University of East Anglia's postgraduate research application portal and the NRPDTP website.

[4-year Norwich Research Park Biosciences Doctoral Training Partnership PhD CASE studentship with Inspiralis Limited. Includes payment of tuition fees, £20,780 annual stipend, and £5,000 per annum Research Training Support Grant.] This fully funded PhD studentship at the University of East Anglia offers an exciting opportunity to investigate how enhancers orchestrate cardiovascular fate using single-cell multi-omics approaches. The project focuses on the earliest stages of vertebrate cardiovascular development, exploring how cardiac and hematoendothelial progenitor cells diverge from a common origin in the lateral plate mesoderm. While key transcription factors are known, the role of non-coding DNA enhancers in regulating gene expression during heart and vessel formation remains less understood. Mutations in these elements are increasingly linked to congenital heart and vascular defects, but their identification and functional validation in the embryo is challenging. The successful candidate will apply advanced single-cell technologies, including scRNA-seq and scATAC-seq, to map the enhancer landscape in the chick embryo, a model system well-suited for imaging and manipulation. Training will be provided in bioinformatics to integrate gene expression and chromatin accessibility data, predict active enhancers, reconstruct gene regulatory networks, and identify conserved elements. Experimental work will include molecular cloning of candidate enhancers into fluorescent reporter constructs for live imaging and CRISPR-based perturbations to test enhancer function in vivo. The project is supervised by a collaborative team: Dr Andrea Munsterberg and Dr Gi Fay Mok at UEA, and Dr Iain Macaulay and Dr Wilfried Haerty at the Earlham Institute. Students will gain expertise in developmental biology, molecular genetics, imaging, and computational biology, and join a vibrant research community through the Norwich Research Park Biosciences Doctoral Training Programme (NRPDTP). The programme includes a three-month professional internship placement (PIPS) and comprehensive training in research and professional skills. Funding covers tuition fees, a £20,780 annual stipend, and a £5,000 per annum research training support grant. Applicants should have at least a UK 2:1 Honours degree (or equivalent) and meet English language requirements (IELTS 6.5 overall, 6 in each category). The position is full-time, starting October 2026. Applications close on 2 December 2026, with interviews scheduled for early February 2026. For more information, contact the supervisors or visit the NRPDTP website.

[Fully funded 4-year PhD studentship: £20,780 stipend per year, payment of tuition fees, and Research Training Support Grant of £5,000 per annum (Research Council Funded).] This fully funded PhD studentship at the University of East Anglia investigates the evolutionary and ecological impact of the Western lifestyle on the human gut microbiome. Supervised by Professor Falk Hildebrand and Drs Wilfried Haerty, Katarzyna Sidorczuk, and Anthony Duncan, the project is based at the Quadram/Earlham Institute within the Norwich Research Park, a vibrant hub for biosciences research. The research focuses on understanding how Western and non-Western populations differ in gut bacterial composition, diversity, and evolutionary patterns, and how these differences may influence disease risk and microbiome resilience. Key objectives include identifying distinguishing patterns between Western and non-Western microbiomes, tracking bacterial adaptation over time and across environments, and exploring the metabolic niches occupied by gut bacteria. The hosting group specializes in metagenomics and microbial evolution, developing bespoke bioinformatic solutions to analyze complex datasets. The PhD programme offers advanced training in evolutionary theory, population genetics, and high-resolution metagenomics, with opportunities to attend international conferences, collaborate with Polish researchers, and undertake a three-month industrial placement. The studentship is part of the Norwich Research Park Biosciences Doctoral Training Programme (NRPDTP), which provides a comprehensive professional development curriculum and a supportive research community. Funding includes a £20,780 annual stipend, full payment of tuition fees, and a £5,000 Research Training Support Grant per year. Applicants must have at least a UK 2:1 Honours degree (or equivalent), prior exposure to statistics and programming, and meet English language requirements (IELTS 6.5 overall, 6.0 in each category). The programme aims for at least two high-impact publications and encourages students to develop their own research questions. Applications close on 2 December 2026, with interviews scheduled for early February 2026. For more information and to apply, visit the UEA postgraduate research portal and the NRPDTP website.