Fully Funded PhD in Organic & Medicinal Chemistry (N,S-Heterocycles, Metal Catalysis, Flow Chemistry) at University of Strasbourg University of Strasbourg in France

The University of Strasbourg in France is offering a fully funded PhD position in Organic & Medicinal Chemistry, starting in October 2026. The research will be conducted in the SOMHet team (Laboratory for Therapeutic Innovation, LIT-UMR 7204) and is funded by ANR PRME (DiverCycloNS). The project focuses on expanding the molecular diversity of N,S-heterocycles via the Doyle-Kirmse reaction, with a strong emphasis on metal catalysis, flow chemistry, and mechanistic studies. These N,S-heterocycles are privileged scaffolds in medicinal chemistry, with applications in drug discovery and molecular synthesis, including drugs like Riluzole, Seroquel, and Amoxicillin.

The research group has developed innovative metal-catalyzed strategies for synthesizing N,S-heterocycles, and this PhD project aims to build on these advances by harnessing the synthetic potential of the Doyle-Kirmse reaction. The project will also address safety challenges associated with diazo reagents by implementing continuous flow chemistry technology, enabling safer generation and manipulation of diazo intermediates. The successful candidate will join a dynamic team at the University of Strasbourg, working at the intersection of organic synthesis, catalysis, and medicinal chemistry.

Applicants should have a strong background in organic chemistry, with demonstrated interest in molecular chemistry, metal catalysis, flow chemistry, and mechanistic studies. Experience in synthetic methodology and a passion for innovative research are highly valued. Candidates must hold a Master's degree (M1 & M2) in a relevant field. The application should include a detailed CV, a one-page cover letter, university marks (M1 & M2), and contact details for two references, all compiled into a single PDF and sent to Dr. Mihaela Gulea ([email protected]) by 20 April 2026.

This opportunity is open to international students, and the position is fully funded. The University of Strasbourg is a leading institution in France, renowned for its research in chemistry and related fields. For more information about the research group and the project, visit the SOMHet team page: SOMHet Team.