This fully funded PhD project at Leeds Beckett University, under the Yorkshire Bioscience Doctoral Training Partnership (YBDTP), offers an exciting opportunity to explore the intersection of nutrition, neuroscience, and physiology. The research focuses on how bitter taste compounds influence metabolism and cognition, with a particular emphasis on the role of genetic variation (such as TAS2R38) in bitter perception. The project will investigate how these genetic and perceptual differences affect metabolic responses and brain activity when consuming bitter foods. As a doctoral researcher, you will gain hands-on experience in molecular biology, human sensory testing, neuroimaging, and cognitive assessment. The project is structured around three integrated studies: (1) lab-based assays in Leeds to identify food-derived bitter compounds that stimulate gut hormone GLP-1 release; (2) a neuroimaging and sensory study at the University of Washington (Seattle), where you will spend three months using fMRI to examine the link between genotype, perception, and brain activation; and (3) a human intervention trial in Leeds to test whether daily consumption of bitters improves glucose regulation and cognitive performance in different genotype groups. You will join a dynamic, multidisciplinary team and benefit from tailored training to support your career in academia, health sciences, or industry. The YBDTP provides a regional doctoral training programme with a strong emphasis on interdisciplinary collaboration, equipping you with research, data analysis, and professional skills relevant to bioscience and related careers. The studentship is open to UK, EU, and international students. Applicants should have (or expect to obtain) at least an upper second-class honours degree or equivalent in a relevant field such as nutrition, physiology, neuroscience, psychology, or any biological, chemical, or physical science or mathematics. Strong analytical skills, enthusiasm for interdisciplinary research, and a willingness to travel are essential. International students must meet the host university's English language requirements and cover costs related to visas, NHS surcharge, and travel. Funding includes a tax-free annual stipend at the UKRI rate (£20,780 for 2025/26 entry), research costs, and tuition fees at the UK rate. A limited number of full studentships are available for exceptional international applicants. The studentship lasts four years and must be completed within this period. To apply, submit an expression of interest form for October 2026 recruitment via the link in the Funding Notes section. You may apply for up to two YBDTP projects. For project-specific questions, contact Professor Lauren Owen at L.j.owen@leedsbeckett.ac.uk. For application process queries, email YBDTP@leeds.ac.uk. The application deadline is 5pm (UK time), Wednesday 7th January 2026. Shortlisted candidates will be invited for interview in February 2026, and successful applicants must confirm acceptance within 10 days of offer. For more information, visit the YBDTP website or the project page .