[Full Home and International tuition fees plus a stipend of £19,215 per annum (2025-26 rate) for 3 years. The fourth year is self-funded for writing-up and research costs.] This fully funded PhD studentship at the University of Plymouth offers an exciting opportunity to investigate the mechanisms of pressure and gas mediated neuroplasticity in the human brain. The project is based at the Brain Research & Imaging Centre (BRIC) and the hyperbaric medicine research charity DDRC, providing access to state-of-the-art facilities for multimodal neuroimaging, brain stimulation, and hyperbaric chamber research. The research aims to systematically test the hypothesis that improvements in cognitive and behavioural performance are driven by neuroplastic changes resulting from altered oxygen concentration and pressure. Hyperbaric oxygen therapy (HBOT) is widely used internationally to treat neurological and psychiatric disorders, but its mechanistic effects on the human brain remain poorly understood, particularly in the UK. This project will build on recent findings to explore how neural markers such as oscillations, cortical excitability, functional connectivity, and neurochemistry respond to changes in oxygen and pressure. The successful candidate will develop expertise in advanced neuroimaging techniques (fMRI, DTI, MRS), brain stimulation methods (TMS, FUS), electrophysiology (EEG), and neurocognitive and physiological assessments. The studentship is supported for three years, covering full Home and International tuition fees and providing a stipend of £19,215 per annum (2025-26 rate). The fourth year is a self-funded writing-up period. Applicants should have a 1st class or high 2.1 bachelor’s degree in a relevant subject, with a master’s degree in neuroscience and experience in coding and human neuroscience research considered advantageous. English language proficiency is required for non-native speakers (IELTS Academic 6.5 overall, minimum 5.5 in each component). The project is supervised by Professor Stephen Hall, Professor Gary Smerdon, Dr Elsa Fouragnan, and Dr Helen McKenna, offering a collaborative and interdisciplinary research environment. The application deadline is 30 January 2026, with interviews to follow shortly after. For informal discussions, candidates are encouraged to contact Professor Stephen Hall. For application details, visit the provided link or the University of Plymouth's admissions webpage.