ETH Zürich invites applications for a PhD position in Electrochemical Sensing for Health Applications (SDC18), embedded within the Horizon Europe ENDOTRAIN Doctoral Training Network. ENDOTRAIN aims to revolutionize the diagnosis and management of adrenal disorders by integrating clinical endocrinology, artificial intelligence, data science, engineering, ethics, and law into digital endocrinology. The successful candidate will join the Department of Mechanical and Process Engineering and the Department of Health Sciences and Technology, benefiting from a unique interdisciplinary research environment at one of Europe’s leading technical universities. The project focuses on nanotechnology-enhanced electrochemical sensors for highly sensitive, selective, and reversible biomarker detection. Research will center on designing and fabricating functional electrode coating materials (nano-enzymes) and surface architectures that enable reversible analyte binding, high signal stability, and resistance to biofouling during long-term operation. The PhD candidate will be co-hosted by the Human-centered Sensing Laboratory (Prof. Andreas Güntner) and the Laboratory of Exercise and Health (Prof. Katrien de Bock), providing access to expertise in sensor engineering and health science. Key tasks include engineering redox-active or affinity-based interfaces (nanoparticles, single-atom isolates, artificial enzymes) with tunable binding kinetics, integrating them with transduction schemes for high sensitivity and selectivity in complex media, and validating these systems in vitro and ex vivo. The candidate will also support in vivo tests in mouse models and clinical trials, with secondments at Imperial College London (electrochemical sensing strategies) and University Hospital Zurich (testing on humans). Applicants must hold a Master’s degree in (Electro-)Chemistry, Chemical Engineering, Materials Science, or a related field, demonstrate strong interest in translational health technologies, and possess excellent English communication skills. Experience in sensor design, nanoparticle fabrication, or single-atom catalysts is desirable. Candidates must not have resided or carried out their main activity in Switzerland for more than 12 months in the 36 months prior to recruitment and must meet Swiss PhD eligibility criteria. Participation in ENDOTRAIN’s interdisciplinary training, including workshops, retreats, and cohort-wide meetings across Europe, is mandatory. ETH Zürich offers a competitive salary according to Swiss National Science Foundation regulations, full social security coverage, travel and secondment budget, and opportunities for international networking, industry exposure, and career development. The university values diversity, sustainability, and an inclusive culture, promoting equality of opportunity and a climate-neutral future. Applications should be submitted via the ETH online portal as a single merged PDF document (cover letter, CV, transcripts, references, and representative research work). Informal inquiries can be directed to Prof. Andreas Güntner ([email protected]). More information about the involved research groups is available at the Human-centered Sensing Laboratory and Laboratory of Exercise and Health websites. Join ETH Zürich and contribute to cutting-edge research in electrochemical sensing for health, with access to world-class facilities, interdisciplinary collaboration, and a vibrant academic community in Switzerland.

This fully funded PhD position at ETH Zürich is part of the ENDOTRAIN MSCA Doctoral Network, focusing on the development of innovative biofluid sampling technologies for localized physiological measurements. The project aims to design and fabricate advanced micromachined platforms, such as microneedles, implantables, and microfluidic systems, enabling minimally invasive and continuous sampling of biofluids like interstitial fluid and muscle tissue. These technologies will facilitate direct analysis of metabolites, hormones, and other biomarkers, with transformative potential for diagnostics and monitoring in sports science, rehabilitation, and muscle-related diseases. As a doctoral researcher, you will work within Work Package 2 of the ENDOTRAIN network, contributing to the innovation and testing of novel data acquisition and aggregation technologies. Specific research tasks include designing microfabricated systems for precise spatial sampling, investigating methods for minimal tissue disruption and high analyte recovery, quantifying analyte concentrations in dynamic physiological states using mouse models and human subjects, and developing models for local production, metabolism, and diffusion of analytes between blood, interstitial fluid, and tissue. The position offers interdisciplinary training and collaboration opportunities, including secondments at the University of Bergen (for validation of sampling strategies) and University Hospital Zurich (for human testing). You will be based at ETH Zürich, one of Europe’s leading technical universities, within the Department of Mechanical and Process Engineering and the Department of Health Sciences and Technology. The structured PhD programme includes mandatory participation in ENDOTRAIN network activities such as workshops, retreats, transferable skills courses, and cohort-wide meetings across Europe. Applicants must hold a Master’s degree in Biomedical Engineering, Physiology, Mechanical Engineering, Materials Science, or a related field, and demonstrate a strong interest in translational health technologies. Excellent English language skills and the ability to collaborate across disciplines are essential. Ideally, candidates will have experience in microfabrication, biocompatible materials, and/or implantable devices. Eligibility requires that candidates have not resided or carried out their main activity in Switzerland for more than 12 months in the 36 months prior to recruitment. Willingness to participate in training activities across Europe is mandatory. The position is fully funded, offering a competitive salary according to Swiss National Science Foundation regulations, full social security coverage, and a travel and secondment budget. Additional benefits include opportunities for international networking, industry exposure, and career development. Applications are accepted year-round, with a latest start date of August 2026. To apply, submit your application via the ETH Zürich job portal, ensuring you meet all eligibility criteria.

ETH Zürich invites applications for a fully funded PhD position in Electrochemical Biomarker Sensing with Artificial Enzyme (SDC18), as part of the prestigious ENDOTRAIN MSCA Doctoral Network. This interdisciplinary project is embedded in Work Package 2 of ENDOTRAIN, focusing on the development of nanotechnology-enhanced electrochemical sensors for highly sensitive, selective, and reversible biomarker detection. The research aims to design and fabricate advanced electrode coating materials (nano-enzymes) and surface architectures that enable reversible analyte binding, high signal stability, and resistance to biofouling during long-term operation. Key tasks include engineering redox-active or affinity-based interfaces (enzymes and nano-enzymes) with tunable binding kinetics, integrating these with transduction schemes for high sensitivity and selectivity in complex media, and validating the technology in controlled in vitro and ex vivo systems. The project also supports in vivo tests in mouse models and clinical trials, bridging fundamental research with translational health applications. The successful candidate will be based at ETH Zürich, one of Europe’s leading technical universities, within the Department of Mechanical and Process Engineering and the Department of Health Sciences and Technology. The position offers a unique blend of engineering, health, and technology research, with secondments at Imperial College London (UK) for electrochemical sensing strategies and University Hospital Zurich (CH) for human testing. Applicants must hold a Master’s degree in (Electro-)Chemistry, Chemical Engineering, Materials Science, or a related field, and demonstrate a strong interest in translational health technologies. Excellent English language skills and the ability to collaborate across disciplines are essential. Experience in sensor design, nanoparticle fabrication, or single-atom catalysts is highly desirable. Candidates must not have resided or carried out their main activity in Switzerland for more than 12 months in the 36 months prior to recruitment, in accordance with MSCA mobility rules. The position is fully funded, offering a competitive salary according to Swiss National Science Foundation regulations, full social security coverage, and a travel and secondment budget. The doctoral programme includes mandatory participation in ENDOTRAIN’s interdisciplinary training, workshops, retreats, transferable skills courses, and cohort-wide meetings across Europe. The appointment is for three years, with the possibility of extension, and the latest start date is August 2026. To apply, candidates should submit their application via the ETH Zürich job portal, including a CV, cover letter, and supporting documents. Applications are accepted year-round. This opportunity provides international networking, industry exposure, and career development in a cutting-edge research environment.

ETH Zürich invites applications for a PhD position in Biofluid Sampling Technologies for Localized Physiological Measurements (SDC19), embedded within the Horizon Europe ENDOTRAIN Doctoral Training Network. ENDOTRAIN aims to revolutionize the diagnosis and management of adrenal disorders by integrating clinical endocrinology, artificial intelligence, data science, engineering, ethics, and law into digital endocrinology. The successful candidate will join a vibrant interdisciplinary environment at the Department of Mechanical and Process Engineering and the Department of Health Sciences and Technology, co-hosted by the Human-centered Sensing Laboratory (Prof. Andreas Güntner) and the Laboratory of Exercise and Health (Prof. Katrien de Bock). This PhD project focuses on developing micromachined platforms for minimally invasive and localized access to biofluids, such as interstitial fluid or muscle tissue, enabling direct and continuous sampling and analysis of metabolites, hormones, and other physiological markers. The research is poised to transform diagnostic and monitoring strategies in sports science, rehabilitation, and muscle-related diseases. Specific tasks include designing and fabricating advanced microfabricated systems (e.g., microneedles, implantables, microfluidics), investigating concepts for minimal tissue disruption and high analyte recovery efficiency, quantifying analyte concentrations dynamically in mouse models and humans, and developing models for local production, metabolism, and diffusion of analytes. The position offers secondments at the University of Bergen (validation of sampling strategy) and University Hospital Zurich (testing of samplers on humans), providing opportunities for international collaboration and practical application. ETH Zürich provides a competitive salary according to Swiss National Science Foundation regulations, full social security coverage, travel and secondment budget, and a supportive, inclusive, and diverse working environment. The PhD student will participate in mandatory interdisciplinary training activities across the ENDOTRAIN network, including workshops, retreats, transferable skills courses, and cohort-wide meetings across Europe. Applicants must hold a Master’s degree in Biomedical Engineering, Physiology, Mechanical Engineering, Materials Science, or a related field, demonstrate strong interest in translational health technologies, possess excellent English skills, and show capacity for interdisciplinary collaboration. Ideally, candidates will have experience in microfabrication, biocompatible materials, and implantables. Eligibility criteria include not having resided or carried out main activity in Switzerland for more than 12 months in the 36 months before recruitment. The application deadline is before August 2026. To apply, submit a single merged PDF via the ETH online portal, including a cover letter, CV, transcripts, references, and representative research work. For informal inquiries, contact Prof. Andreas Güntner at [email protected]. More information about the research groups can be found at the Human-centered Sensing Laboratory and Laboratory of Exercise and Health websites. ETH Zürich is committed to diversity, sustainability, and excellence in research and education.