Mats Karlsson at Uppsala Universitet - Research Interests, Publications & Academic Profile - ApplyKite

Mats Karlsson

Professor

Uppsala University

Sweden

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Research Interests

Biostatistics

70%

Pharmacology

100%

Pharmacometrics

60%

Psychometric

40%

Propensity Score Analysis

40%

Pharmacoepidemiology

30%

Dose Optimization

30%

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Articles20

Item performance of the scale for the assessment and rating of ataxia in rare and ultra‐rare genetic ataxias

Year:

2024

Covariate modeling in pharmacometrics: General points for consideration

Year:

2024

Predicting the Long‐Term Effects of Therapeutic Neutralization of Oncostatin M on Human Hematopoiesis

Year:

2024

Quantitative Comparisons of Progressive Supranuclear Palsy Rating Scale Versions Using Item Response Theory

Year:

2024

Evaluation of model‐integrated evidence approaches for pharmacokinetic bioequivalence studies using model averaging methods

Year:

2024

Development and comparison of model‐integrated evidence approaches for bioequivalence studies with pharmacokinetic end points

Year:

2024

Evaluation of covariate effects in item response theory models

Year:

2024

Item response theory analysis of daytime sleepiness as a symptom of obstructive sleep apnea

Year:

2024

Properties of the full random‐effect modeling approach with missing covariate data

Year:

2024

Comparison of Two Methods for Determining Item Characteristic Functions and Latent Variable Time-Course for Pharmacometric Item Response Models

Year:

2024

Evaluation of the Effect of Erenumab on Migraine‐Specific Questionnaire in Patients with Chronic and Episodic Migraine.

Year:

2023

Assessment of ibrutinib scheduling on leukocyte, lymph node size and blood pressure dynamics in chronic lymphocytic leukemia through pharmacokinetic‐pharmacodynamic models

Year:

2023

A multistate modeling and simulation framework to learn dose–response of oncology drugs: Application to bintrafusp alfa in non‐small cell lung cancer

Year:

2023

Relationship between factor VIII levels and bleeding for rFVIII‐SingleChain in severe hemophilia A: A repeated time‐to‐event analysis

Year:

2023

Multistate Pharmacometric Model to Define the Impact of Second‐Line Immunotherapies on the Survival Outcome of the IMpower131 Study

Year:

2023

Comparison of Seven Non-Linear Mixed Effect Model-Based Approaches to Test for Treatment Effect

Year:

2023

Assessing Prolongation of the Corrected QT Interval with Bedaquiline and Delamanid Coadministration to Predict the Cardiac Safety of Simplified Dosing Regimens

Year:

2022

Improved Confidence in a Confirmatory Stage by Application of Item-Based Pharmacometrics Model: Illustration with a Phase III Active Comparator-Controlled Trial in COPD Patients

Year:

2022

Detecting placebo and drug effects on Parkinson's disease symptoms by longitudinal item‐score models

Year:

2021

Comparison of covariate selection methods with correlated covariates: prior information versus data information, or a mixture of both?

Year:

2020

Collaborators3

Nick Holford

University of Auckland

NEW ZEALAND

Matthis Synofzik

Professor

Hertie Institute for clinical brain research

GERMANY

Lena Friberg

Professor

Uppsala University

SWEDEN

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