Stephan Ludwig at Westfälische Wilhelms Universität Münster Medizinische Fakultät - Research Interests, Publications & Academic Profile

Stephan Ludwig

Full Professor and Director

Westfälische Wilhelms Universität Münster Medizinische Fakultät

Germany

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Research Interests

Virology

100%

Immunology

80%

Sars-cov-2

100%

Antiviral Therapy

40%

Inflammatory Biology

40%

Influenza Research

30%

Vaccinology

20%

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Recent Grants

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CoIMMUNE - Verwendung von humanen Lungenexplantaten zur prä-klinischen Evaluation von immunmodulatorischen Ansätzen zur Behandlung von COVID-19 ausgelöst durch SARS-CoV-2

Open Date: 2020-07-01

Close Date: 2021-12-31

Grant: Close

CoPREDICT - Covid-19 - Evaluation von Präventionstrategien durch agentenbasierte Simulationen

Open Date: 2020-06-01

Close Date: 2021-11-30

Grant: Close

EPIPREDICT - Benutzerorientierte Erweiterung und Automatisierung der agentenbasierten Software zur erregerspezifischen Modellierung vom Epidemien

Open Date: 2020-03-01

Close Date: 2022-02-28

Grant: Close

The role of MAPK pathways in SARS CoV-2 infection and COVID-19 disease (B13#)

Open Date: 2020-01-01

Close Date:

Grant: Close

KFO 342: Organ Dysfuncion During Systemic Inflammation

Open Date: 2019-01-01

Close Date:

Articles17

The host-targeted antiviral drug Zapnometinib exhibits a high barrier to the development of SARS-CoV-2 resistance

Article Link

Year:

2024

Small Spleen Peptides (SSPs) Shape Dendritic Cell Differentiation through Modulation of Extracellular ATP Synthesis Profile

Article Link

Year:

2024

MEK inhibitors as novel host-targeted antivirals with a dual-benefit mode of action against hyperinflammatory respiratory viral diseases

Article Link

Year:

2023

Importance of ACE2 for SARS-CoV-2 Infection of Kidney Cells

Article Link

Year:

2023

Pathophysiological Mechanisms of Cardiac Dysfunction in Transgenic Mice with Viral Myocarditis

Article Link

Year:

2023

Cell-intrinsic genomic reassortment of pandemic H1N1 2009 and Eurasian avian-like swine influenza viruses results in potentially zoonotic variants

Article Link

Year:

2023

Surrogate Virus Neutralisation Test Based on Nanoluciferase-Tagged Antigens to Quantify Inhibitory Antibodies against SARS-CoV-2 and Characterise Omicron-Specific Reactivity in a Vaccination Cohort

Article Link

Year:

2023

Glycolytic interference blocks influenza A virus propagation by impairing viral polymerase-driven synthesis of genomic vRNA

Article Link

Year:

2023

Impaired humoral immunity to BQ.1.1 in convalescent and vaccinated patients

Article Link

Year:

2023

Influenza A virus replication has a stronger dependency on Raf/MEK/ERK signaling pathway activity than SARS-CoV-2

Article Link

Year:

2023

Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages.

Article Link

Year:

2022

The MEK1/2 Inhibitor ATR-002 (Zapnometinib) Synergistically Potentiates the Antiviral Effect of Direct-Acting Anti-SARS-CoV-2 Drugs

Article Link

Year:

2022

3D <i>ex vivo</i> tissue platforms to investigate the early phases of influenza A virus- and SARS-CoV-2-induced respiratory diseases.

Article Link

Year:

2022

Virus Infection and Systemic Inflammation: Lessons Learnt from COVID-19 and Beyond

Article Link

Year:

2022

<i>Hypericum perforatum</i> and Its Ingredients Hypericin and Pseudohypericin Demonstrate an Antiviral Activity against SARS-CoV-2

Article Link

Year:

2022

Rapid SARS-CoV-2 Adaptation to Available Cellular Proteases

Article Link

Year:

2022

SARS-CoV-2 infects and replicates in photoreceptor and retinal ganglion cells of human retinal organoids.

Article Link

Year:

2022

Collaborators18

Anja E. Hauser

GERMANY

M. Zeeshan Chaudhry

The University of Queensland Diamantina Institute

AUSTRALIA

Carsten Theiss

Ruhr-Universität Bochum

GERMANY

Giuliano Ciarimboli

University Hospital Münster

GERMANY

Morris Baumgardt

GERMANY

Ursula Rescher

University of Münster

GERMANY

Alexander Mellmann

University of Muenster

GERMANY

Susann Kummer

Head of Project Group - AG4 Stability and Persistence of Risk Group 4 Viruses

Robert Koch Institute

GERMANY

Sefer Elezkurtaj

Charité - Universitätsmedizin Berlin

GERMANY

Cornelius Faber

GERMANY

Christine Goffinet

Associate Professor

Charité - Universitätsmedizin Berlin

GERMANY

Yotam Menuchin-Lasowski

Max Planck Institute of Molecular Cell Biology and Genetics

GERMANY

Karin Klingel

Head of Cardiopathology/Infection Pathology

University Hospital

GERMANY

Wolfgang A. Linke

GERMANY

Benedikt Obermayer

Berlin Institute of Health at Charité - Universitätsmedizin Berlin

GERMANY

Georg Hempel

GERMANY

Anna Pascual Reguant

Charité - Universitätsmedizin Berlin

GERMANY

Markus Landthaler

Humboldt-Universität zu Berlin

GERMANY

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