Amyloid-beta Structure and Membrane Interactions in Alzheimer’s Disease (PhD Studentship) Queen Mary University of London in United Kingdom

Coming soon at the Astbury Centre for Structural Molecular Biology, The University of Leeds: two postdoctoral positions and one PhD position will soon be advertised. The research themes mentioned are outer membrane protein assembly mechanisms and cryoEM of amyloid. One postdoc and one PhD student will be linked to outer membrane protein assembly mechanisms, while one postdoc will focus on cryoEM of amyloid. The post is shared by Sheena Radford, Astbury Professor of Biophysics at The University o...

Research Associate on the structural biology of bacterial secretion systems at Imperial College London (South Kensington Campus, London, UK). This is a postdoctoral research opening in the Department of Infectious Disease , working with Prof Harry Low and the Low Lab on the molecular mechanism of bacterial secretion systems, including the Tad and Type 4 pilus systems. The project is strongly focused on structural biology , cryo-electron microscopy (SPA, in-situ SPA, tomography), TIRF microscopy ...

PhD opportunity at The Francis Crick Institute, London, United Kingdom in regulatory switching of a microtubule motor-scaffold complex with Dr Sami Chaaban. This funded PhD project focuses on how microtubule motors , especially kinesins , organize microtubules and position regulatory proteins during cell division. The project asks how interactions with regulatory partners switch kinesins between functional states and how these changes shape specialized microtubule structures. Research methods in...

PhD opportunity in mechanism of transcription-coupled splicing at the Medical Research Council Laboratory of Molecular Biology in Cambridge, United Kingdom , supervised by Dr Suyang Zhang . The project focuses on how RNA polymerase II and the spliceosome communicate during co-transcriptional splicing to ensure accurate gene expression in eukaryotic cells. The lab studies the molecular mechanisms coordinating transcription and pre-mRNA splicing in human cells, including direct interactions betwee...

PhD opportunity at The Francis Crick Institute, London, United Kingdom in structural biology, virology, biochemistry, biophysics, and molecular biology . This funded PhD project, supervised by Dr I Taylor , focuses on the ZAP antiviral response and how the proteins ZAP, KHNYN, and Trim25 assemble into molecular complexes that recognize viral RNA and trigger RNA degradation. The project aims to uncover the structure and mechanism of this antiviral system using protein purification, RNA-binding as...