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About this position

?? Looking for a PhD student! If you are interested, send your CV (remeber to add General Data Protection Regulation consent) and motivation letter to my e-mail: ?? [email protected]
Deadline: 15.08.2025
Selected candidates will be invited to the interview.

Localization: Nalecz Institute of Biocybernetics and Biomedical Engineering Polish Academy of Sciences , Warsaw, Poland.
Start: October 2025 (One-month pre-training is optional).
Stipend: 5000 PLN (c.a. 4500 PLN net).
Duration: 4 years.
Benefits: 8 weeks of holidays, multisport card, medical package.

?? Topic:
Pseudomonas aeruginosa is a common opportunistic human pathogen. One of the ways how P. aeruginosa causes infection is through Quorum Sensing (QS) - a type of cell signaling pathway that initiates the production of virulence factors. QS is a phenomenon of chemical communication between bacterial cells involving the synthesis and secretion of signaling molecules called autoinducers (AIs). In the case of P. aeruginosa, the most known AIs are N-acyl-homoserine lactones (AHLs), 2-heptyl-3-hydroxy-4-quinolon (PQS) and 2-(2-hydroxyphenyl)-thiazole-4-carbaldehydes (IQS). The aim of this project is to construct an electrochemical sensor based on short DNA fragments to determine the PQS and IQS concentrations. Project financed by NCN National Science Centre Sonata bis 2023/50/E/ST5/00347.

?? To do:
1. Selection of DNA strands as bioreceptors for IQS and PQS 2. Optimization of surface functionalization with selected DNA strands 3. Physico-chemical characterization of DNA-functionalized surfaces 4. Evaluation of metrological parameter of DNA-based sensors
????? ????? Requirements:
1. MSc in Chemistry, Biomedical Engineering, Nanotechnology, Chemical Technology, Materials Science or similar; 2. Experience in surface functionalization and nanomaterials manipulation; 3. Experience in usage of electrochemical methods (CV, DPV) and spectrophotometric methods (FTIR, UV-vis); 4. Experience in analytical sciences: knowledge of techniques and good laboratory skills; 5. Basic knowledge of statistical methods; 6. Good reading and writing in English.

Funding details

Project financed by NCN National Science Centre Sonata bis 2023/50/E/ST5/00347

How to apply

Send CV and motivation letter to [email protected]

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