PhD in Modelling Deformability and Collapse in Gels of Red Blood Cells University of Bristol in United Kingdom

This PhD project at the University of Bristol's School of Physics focuses on modelling the deformability and collapse of gels formed by red blood cells (RBCs). Physical gels, composed of networks of micron-scale particles, are widely used in various industries due to their stability, but their eventual collapse under gravity is not well understood. The project aims to investigate how the microstructure and mechanical properties of gel constituents, particularly RBCs, influence the collapse process. RBCs serve as a biologically relevant model system because of their high deformability and tendency to form gel-like aggregates, whose collapse dynamics are affected by cell shape, rigidity, and intercellular interactions.

The research will employ a dual approach: experimental measurements using confocal microscopy and computational studies via coarse-grained molecular dynamics simulations. The findings are expected to have implications for soft matter physics, biomedical diagnostics, and the design of new materials. Supervision is provided by Dr Francesco Turci (simulations) and Dr Alexis Darras (experiments), with additional expertise from faculty in red blood cell biology, clinical science, and computational physics.

The project is embedded in a vibrant, supportive graduate research community, offering comprehensive training, career development, and pastoral support. Funding is available for home students (covering tuition, stipend, and training expenses), with a limited number of fully-funded places for outstanding international candidates. Applicants should have a strong background in physics or a related field, and meet the university's English language requirements.

The application deadline is 19 January 2026. Interested candidates should apply online, submitting a CV, personal statement, and transcripts, and specify 'Bristol Physics Research Scholarships' as the funding source.