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Stuart Casson

11 months ago

PhD in Molecular Biology: The Role of Long Non-coding RNAs in Guard Cell Function and Development (BBSRC Yorkshire Bioscience DLA Programme) University of Sheffield in United Kingdom

Degree Level

PhD

Field of study

Molecular Biology

Funding

Funded PhD Project (Students Worldwide)

Deadline

Expired

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Country

United Kingdom

University

University of Sheffield

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Keywords

Molecular Biology
Plant Biology
Biology
Gene Expression
Plant Physiology
Cell Signaling
Mutation
Transgenic Technology
Histone Modification
Abiotic Stress
Non-coding Rna
Bioscience
Carbon Dioxide

About this position

This fully funded PhD position at the University of Sheffield, offered through the BBSRC Yorkshire Bioscience Doctoral Training Partnership (YBDTP), focuses on the molecular role of long non-coding RNAs (IncRNAs) in plant guard cell function and development. The project is led by Dr Stuart Casson, Dr Dan Bose, and Prof Julie Gray, whose labs have identified IncRNAs highly expressed in guard cells—cells that regulate gas exchange in plants. At least one of these IncRNAs is crucial for plant responses to increased carbon dioxide, and the research aims to translate this knowledge to improve crop resilience to abiotic stress.

The successful candidate will investigate how these IncRNAs regulate plant responses to various abiotic signals, including CO2, light, humidity, and plant hormones. The project involves using genetic methods such as mutants and transgenics to manipulate IncRNA expression, followed by analysis of plant responses. Advanced molecular techniques, gene expression analysis, chromatin modification studies, and plant physiological assays will be employed to understand the mechanisms by which IncRNAs influence plant abiotic responses. The YBDTP provides a vibrant, interdisciplinary training environment across several Yorkshire and Teesside universities, with opportunities for collaboration, professional development, and international conference participation.

Applicants should have a strong background in molecular biology or genetics and an interest in cell signalling and plant-environment interactions. The studentship is open to UK, EU, and international students, with a competitive selection process and limited full studentships for exceptional international candidates. The award covers a four-year UKRI stipend, research costs, and tuition fees at the UK rate. International students must cover their own visa, NHS surcharge, and travel costs.

The application deadline is 7 January 2026, and shortlisted candidates will be interviewed in February 2025. For more information or to apply, visit the YBDTP website or contact the supervisors directly.

Funding details

Funded PhD Project (Students Worldwide)

What's required

Applicants must have, or expect to gain, at least an upper second-class honours degree or equivalent in a biological, chemical, or physical science, or mathematics. Experience in molecular biology or genetics is ideal. International students must meet the host university's English language requirements. The programme welcomes applicants from all backgrounds, especially those underrepresented in science. Not all projects will be funded; selection is competitive.

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Professors

Dr at School of Biosciences

University Name
Country flag

United Kingdom

Research Interests

Environmental Chemistry

Botany

Photosynthesis

Plant Physiology

Electron Transfer

Dr at School of Biosciences

University Name
Country flag

United Kingdom

Research Interests

Non-coding Rna

Gene Expression

Cell Signaling

Molecular Biology

Plant Physiology

Prof at School of Biosciences

University Name
Country flag

United Kingdom

Research Interests

Botany

Crop Science

Plant Biology

Plant Physiology

Cell Wall