Postdoctoral in Molecular Microbiology and PhD in Experimental Microbiology on Mycobacterium abscessus University of Basel in Switzerland

Two full-time research openings are available at the Department of Biomedicine, University of Basel, in Basel, Switzerland. The post advertises one Postdoctoral in Molecular Microbiology position and one PhD in Experimental Microbiology position, both centered on Mycobacterium abscessus, a difficult-to-treat bacterial pathogen.

The postdoctoral project focuses on molecular microbiology, including pooled CRISPRi library generation and screening across multiple bacterial genetic backgrounds and infection-relevant conditions. The work will use viability-based selection strategies to quantify bacterial killing at scale and integrate these results with genomic data from more than 1,000 clinical isolates to develop predictive models linking genotypes, tolerance phenotypes, and clinical outcomes.

The PhD project is in experimental microbiology and involves high-content live-cell imaging to measure bacterial viability under antibiotic exposure across diverse conditions and clinical isolates. The student will collaborate closely with postdoctoral researchers and combine imaging data with CRISPRi and transposon mutagenesis screen results to identify molecular mechanisms and genotypes underlying tolerance phenotypes. The work emphasizes systematic experimental design, large-scale dataset generation, and quantitative analysis of single-cell time-kill dynamics.

The positions are part of the multidisciplinary Lucas Boeck Lab within the Department of Biomedicine, an internationally recognized research environment in Basel. The post highlights access to modern infrastructure and state-of-the-art equipment. No deadline, stipend amount, tuition information, or formal eligibility details are provided in the post itself; applicants are directed to the job offer linked in the comments.