Postdoctoral Researcher in SYNGAP1 Disease Modeling and Therapeutic Discovery Sapienza University of Rome in Italy

A postdoctoral researcher position is available in the Department of Physiology and Pharmacology at Sapienza University of Rome, Italy, focusing on in vitro modeling of SYNGAP1-related syndrome. The research aims to develop and characterize human in vitro models of SYNGAP1, investigate patient-relevant mutations and their molecular and cellular impacts, and explore drug repositioning strategies using mechanistic and translational approaches. The project integrates disease modeling, functional genomics, and therapeutic discovery in a collaborative, interdisciplinary environment.

Preferred skills for applicants include gene editing (CRISPR/Cas9), human iPSC maintenance and differentiation, RNA sequencing and transcriptomic analysis, RT-PCR/qPCR, and immunofluorescence and imaging. However, these are not mandatory. Strong motivation, curiosity, and a keen interest in neurodevelopmental disorders and translational research are highly valued. The position is full-time for two years, with a flexible start date. No specific funding or stipend details are provided in the announcement.

Interested candidates should contact Bernadette Basilico at [email protected], submitting a CV and a brief statement of research interests. The research environment offers opportunities to work on cutting-edge topics such as SYNGAP1, disease modeling, functional genomics, and therapeutic discovery, making it ideal for candidates interested in neuroscience, biology, and medical science.