Bart Vanhaesebroeck

UMC Utrecht is advertising a postdoctoral position in the group of Madelon Maurice as part of the international Cancer Grand Challenges REWIRE-CAN consortium. The project focuses on colorectal cancer , WNT signalling , cell signalling dynamics , and therapeutic vulnerability discovery using patient-derived organoids , advanced imaging, genomics, proteomics, and in vivo models. The research aims to go beyond conventional pathway inhibition and instead develop innovative therapeutic strategies that push cancer cells beyond their tolerated signalling range. The postdoctoral researcher will work in a highly collaborative international team spanning drug discovery, cancer biology, AI, organoid technology, and translational preclinical models. Ideal candidates should hold a PhD in cancer biology , signalling mechanisms , molecular/cell biology , organoid research , or a related biomedical field. The post is especially relevant for researchers interested in colorectal cancer, signalling modulation, organoid-based disease modelling, and translational oncology. The post is linked to the REWIRE-CAN consortium, which is focused on rewiring cancer cells by manipulating signalling pathways and testing novel therapeutic approaches in preclinical systems. The announcement does not state a deadline, salary, or specific funding amount in the post content provided. To apply, use the vacancy link and follow the instructions on the UMC Utrecht careers page. Review the full vacancy for required documents and any additional eligibility or selection criteria.