Elisabeth Nyström

Karolinska Institutet in Stockholm, Sweden is recruiting for two research positions in the Elisabeth Nyström lab: a PhD student and a Postdoctoral researcher in intestinal mucosal immunology , mucus biology , and goblet cell biology . The research focuses on how intestinal mucosal barriers are maintained and what happens when they fail, with an emphasis on mucus-producing goblet cells, epithelial barrier function, and host–microbe interactions in health and disease. The PhD project will investigate goblet cell and mucus dynamics during infection using in vivo models and live tissue analysis. The postdoctoral project will validate and apply a genetic targeting strategy to functionally characterize specific goblet cell subtypes in vivo. The lab uses interdisciplinary approaches including molecular biology, genetics, omics, single-cell RNA sequencing, proteomics, mass spectrometry, advanced imaging, and ex vivo live intestinal tissue analysis. The group works in a collaborative environment at Karolinska Institutet and Center for Molecular Medicine, with close interaction with the groups of Eduardo Villablanca, Camilla Engblom, and Gustavo Monasterio Ocares. Funding: both positions are fully funded. The PhD is a doctoral studentship with salary for up to 4 years full-time. The postdoc is a full-time temporary position. Eligibility highlights: the PhD requires a relevant master’s degree or equivalent eligibility for doctoral education, English proficiency, documented experimental lab experience, mouse handling certification, and preferably experience with intestinal infection models, scRNA-seq, bioinformatics, proteomics, or imaging. The postdoc requires a PhD or equivalent, strong experience with complex mouse strains and genetically modified models, familiarity with intestinal physiology, and preferably experience with imaging, FACS, omics, and bioinformatics. Application: apply through the Varbi recruitment system using the position-specific links. The PhD deadline is 2026-05-22 and the postdoctoral deadline is 2026-05-29.

Karolinska Institutet in Stockholm, Sweden is recruiting for two fully funded research positions in the Elisabeth Nyström lab: a PhD student and a Postdoctoral researcher in intestinal mucosal immunology , with a strong focus on mucus biology , goblet cells , and epithelial barrier function . The PhD project will investigate how diverse mucus-producing cell populations shape mucus properties and how changes in cell composition influence mucus function through post-translational modifications of mucus proteins. The work uses intestinal infection models , single-cell RNA sequencing , ex vivo mucus analysis , mass spectrometry , and biochemical validation. The postdoctoral project will establish and validate a genetic targeting strategy to specifically target goblet cell subtypes in vivo and functionally analyze their role in mucus- and goblet cell-mediated defense mechanisms. Methods include advanced imaging, transcriptomics, proteomics, and ex vivo tissue analysis. The lab works in a highly collaborative environment at Karolinska Institutet and the Center for Molecular Medicine, with close interactions with the groups of Eduardo Villablanca , Camilla Engblom , and Gustavo Monasterio Ocares . The research is interdisciplinary, combining molecular biology, genetics, biochemistry, physiology, and omics approaches. Eligibility highlights: PhD applicants need a relevant master’s degree, documented experimental lab experience, mouse handling certification, and English proficiency. Postdoc applicants need a PhD in a relevant field plus strong experience with complex mouse strains and genetically modified models. Experience with intestinal infection models, scRNA-seq, proteomics, imaging, FACS, and bioinformatics is advantageous. Funding: both positions are fully funded. The PhD is a doctoral studentship with salary for up to 4 years full-time. The postdoc is a full-time temporary employment. Application window: the postdoctoral position closes on 2026-05-29 . The PhD position closes on 2026-05-22 . Applications are submitted through the Varbi recruitment system.