PhD Position in Tumor Immunology of Peritoneal Metastasis at Amsterdam UMC

Amsterdam UMC is offering a fully funded PhD position in Tumor Immunology of Peritoneal Metastasis, focusing on colorectal cancer with peritoneal metastases—a patient group with poor prognosis and limited effective therapies. This KWF-funded project investigates the role of tumor-associated glycan structures, particularly sialic acids, in immune suppression and explores glycan inhibition as a strategy to restore anti-tumor immunity. The research is translational, utilizing patient material and in vivo models to test hypotheses and develop new therapeutic approaches. The successful candidate will join the Department of Molecular Cell Biology and Immunology, located in the O|2 Lab Building at the VU/Amsterdam UMC campus, which boasts excellent cytometry and imaging core facilities. The research group, led by Dr. Sandra van Vliet, collaborates with Dr. K. Lenos, Dr. J. Grootjans, and Prof. Dr. J. Tuynman, integrating expertise from experimental oncology, gastroenterology, and surgery. The project involves advanced immunological and cell biological techniques, including flow cytometry and tumor slice cultures, and offers opportunities to present findings at national and international conferences, supervise BSc/MSc students, and contribute to departmental teaching in immunology and biochemistry. Applicants must hold a master's degree in biomedical sciences or an equivalent field, demonstrate strong analytical and problem-solving skills, and have experience with flow cytometry and/or human tissue slice cultures. Willingness to work with animal models is required, with an article 9 certificate and prior experience considered advantageous. Candidates should be proactive, flexible, able to work independently and collaboratively, and possess excellent English communication skills. Medical doctors are not eligible for this position. The position is fully funded, with a salary scale OIO (€3,108–€3,939 gross per month, depending on education and experience), a year-end bonus, holiday hours, pension accrual, and travel reimbursement. The initial contract is for 12 months, with the intention to extend for a total of 4 years. Amsterdam UMC offers a diverse, inclusive, and international research environment, supporting career development and scientific excellence. To apply, candidates should submit their application via the Amsterdam UMC vacancies portal, including a CV and motivation letter. For further information, contact Dr. Sandra van Vliet at [email protected]. Applications are reviewed continuously until the position is filled, with a final deadline of January 18, 2026.