Jochen Hub

PhD Opportunity in Computational Biophysics at Saarland University Saarland University, a leading research institution in Germany, invites applications for a fully funded PhD position in the group of Professor Jochen Hub within the Theoretical Biophysics department. This position is part of the EU-funded Doctoral Network (DN) "WATER" under the Marie Sklodowska-Curie actions (HORIZON-MSCA-2024-DN-01-01), offering a unique opportunity to join a cohort of 13 PhD students across Europe, jointly trained in cutting-edge biophysical techniques. The research focuses on computational biophysics, specifically the mechanisms of membrane fusion—a process central to viral infection, molecular signaling, and drug delivery by lipid nanoparticles. The Hub group employs advanced molecular dynamics simulations and machine learning to study how proteins, biomembranes, and small molecules interact to enable key biological functions. The successful candidate will develop and apply free energy calculation techniques to investigate how membrane composition, membrane-active proteins, and hydration influence membrane fusion. The project aims to advance our understanding of the fusion pathway and to develop strategies for manipulating fusion in health and disease contexts. The PhD project is purely computational but involves close collaboration with experimental partners, particularly at EPFL (Lausanne, Switzerland). Two secondments are planned: one at a research-oriented startup in Lausanne and another with a computational academic partner. The position is funded for three years, with salary and allowances provided according to EU Marie Curie regulations, including mobility and, if applicable, family allowances. Eligibility and Requirements: Applicants must hold (or be near completion of) a Master's degree or equivalent in physics, physical chemistry, or biophysics. Experience in computational science, programming (C/C++ or Python), or shell scripting is advantageous. Strong communication skills are essential due to the collaborative nature of the project. Importantly, candidates must not have resided in Germany for more than 12 months in the past three years, in accordance with Marie Curie mobility rules. Saarland University encourages applications from women and individuals with disabilities. Application Process: Submit your application as a single PDF to [email protected] by February 8, 2026. The application should include your CV, publication record, all academic certificates (including transcripts), university entrance exam results (German Abitur or equivalent), and the names of two references. Documents will be destroyed after a five-month holding period. For more information about the group, visit the group website . Saarland University is committed to increasing the proportion of women in science and fostering an inclusive research environment. Start date: As soon as possible.