This PhD position at Eindhoven University of Technology focuses on the long-term monitoring of sleep disorder symptoms, specifically narcolepsy, using digital tools and mHealth applications. The project is a collaboration between TU/e, Sleep Center Kempenhaeghe, and Takeda, aiming to improve low-obtrusive, scalable monitoring and management of narcolepsy symptoms. Narcolepsy is a chronic sleep disorder with a wide range of symptoms, including excessive daytime sleepiness, cataplexy, hallucinations, sleep paralysis, and fragmented sleep, as well as cognitive and mood disturbances. Current questionnaires do not adequately capture the full spectrum or variability of symptoms, creating a need for advanced monitoring tools. The research will utilize the Narcolepsy Monitor, a digital tool developed by Kempenhaeghe, to analyze symptom clusters and quantify disease burden dynamics over time. The project will also integrate wearable sensor data with self-reported data to enhance monitoring accuracy and reduce user burden. Another key aspect is understanding the preferences of patients and healthcare professionals in monitoring and co-creating dashboards tailored to their needs. The successful candidate will join a multidisciplinary team with expertise in sleep medicine, longitudinal monitoring, and digital health technology, working within the Advanced Sleep Monitoring research group (Biomedical Diagnostics lab, Electrical Engineering) and the Human Technology Interaction group (Industrial Engineering & Innovation Sciences). The position offers full-time employment for four years, competitive salary and benefits, and opportunities for professional development. Applicants should have a master’s degree in a relevant field, experience with statistical modelling and clinical data collection, and fluency in English and Dutch. The application process is online, and the position will remain open until filled.

This PhD position at Eindhoven University of Technology focuses on advancing positive airway pressure (PAP) therapy for sleep apnea, specifically obstructive sleep apnea (OSA), a common disorder that disrupts breathing during sleep and increases risks for cardiovascular disease, diabetes, depression, and daytime sleepiness. The project is based in the Biomedical Diagnostic (BM/d) Lab, part of the Signal Processing Systems group in the Electrical Engineering department, and involves collaboration with the Center for Sleep Medicine Kempenhaeghe and Philips Sleep & Respiratory Care. The research aims to improve understanding of PAP therapy's effects on sleep quality and patient outcomes, with a particular emphasis on both objective and subjective measurements during home-based auto-titration periods. The candidate will set up and run a clinical data collection trial, analyze physiological and subjective sleep data, and apply advanced statistical and data analysis methods to relate these findings to therapeutic outcomes. The project is embedded within the Eindhoven MedTech Innovation Center (e/MTIC), a public-private partnership focused on high-tech health innovations, especially in sleep, perinatal, and cardiovascular fields. The BM/d lab has a strong track record in electrophysiological signal processing, physiological modelling, and biosignal analysis. The position offers full-time employment for four years, with a competitive salary and benefits according to Dutch university standards, including pension, paid leave, bonuses, and support for international candidates. Applicants should have a MSc in a relevant field, experience with biomedical trials and physiological signal processing, and fluency in English and Dutch. The successful candidate will work in a multidisciplinary, international environment, with opportunities for teaching and professional development. Applications are accepted online until the position is filled, with a formal screening process in place.