The Max Planck Institute for Heart and Lung Research in Bad Nauheim, Germany, is offering a funded PhD position in RNA/protein biochemistry and molecular biology, focusing on the study of genetic compensation and transcriptional adaptation. The position is based in the Department of Developmental Genetics (Stainier lab), where recent discoveries have highlighted a novel form of genetic compensation termed transcriptional adaptation. This phenomenon involves mutant mRNA decay leading to the modulation of related gene expression and varying degrees of phenotypic rescue, observed in model organisms such as zebrafish, mouse, C. elegans, and humans.

The research will address fundamental questions about the nature and trafficking of mRNA decay fragments and their role in regulating related genes. The lab utilizes cutting-edge technologies and model systems, supported by advanced core facilities in sequencing, proteomics, bioinformatics, cytometry, microscopy, and small animal imaging. The Max Planck Society is committed to diversity and encourages applications from all backgrounds, including individuals with disabilities.

Applicants should have a Master's degree in biology, biochemistry, genetics, or a related field, with a focus on molecular biology, cell biology, biochemistry, and/or genetics. Knowledge of RNA and/or protein biochemistry and molecular biology is advantageous. The position is funded, though specific financial details are not provided. To apply, candidates should submit references, a CV, and a research statement to Prof. Dr. Didier Stainier and also apply to the International Max Planck Research School for Molecular Organ Biology (IMPRS-MOB).