The Max Planck Institute for Heart and Lung Research in Bad Nauheim, Germany, is offering a funded PhD position in RNA/protein biochemistry and molecular biology, focusing on the study of genetic compensation and transcriptional adaptation. The position is based in the Department of Developmental Genetics (Stainier lab), where recent discoveries have highlighted a novel form of genetic compensation termed transcriptional adaptation. This phenomenon involves mutant mRNA decay leading to the modulation of related gene expression and varying degrees of phenotypic rescue, observed in model organisms such as zebrafish, mouse, C. elegans, and humans. The research will address fundamental questions about the nature and trafficking of mRNA decay fragments and their role in regulating related genes. The lab utilizes cutting-edge technologies and model systems, supported by advanced core facilities in sequencing, proteomics, bioinformatics, cytometry, microscopy, and small animal imaging. The Max Planck Society is committed to diversity and encourages applications from all backgrounds, including individuals with disabilities. Applicants should have a Master's degree in biology, biochemistry, genetics, or a related field, with a focus on molecular biology, cell biology, biochemistry, and/or genetics. Knowledge of RNA and/or protein biochemistry and molecular biology is advantageous. The position is funded, though specific financial details are not provided. To apply, candidates should submit references, a CV, and a research statement to Prof. Dr. Didier Stainier and also apply to the International Max Planck Research School for Molecular Organ Biology (IMPRS-MOB).

The Max Planck Institute for Heart and Lung Research in Bad Nauheim, Germany, is offering a fully funded PhD position in the Department of Developmental Genetics (Stainier lab). The research focuses on the molecular and cellular mechanisms underlying genetic compensation and transcriptional adaptation, particularly the role of mRNA decay fragments in gene expression and phenotypic rescue. This is a rapidly evolving field with significant implications for understanding cardiovascular and pulmonary diseases. The successful candidate will join an interdisciplinary team investigating genetic compensation in various model organisms, including zebrafish, mouse, C. elegans, and humans. The research utilizes advanced molecular biology, RNA/protein biochemistry, and state-of-the-art technologies such as next-generation sequencing, proteomics, and bioinformatics. The Max Planck Institute provides access to cutting-edge core facilities and fosters an international, diverse research environment. Applicants must have a Master's degree in biology, biochemistry, genetics, or a related field, with a strong background in molecular biology and RNA/protein biochemistry. Experience with zebrafish, mouse, or C. elegans is advantageous. Candidates should be highly motivated and prepared to contribute to innovative research in genetic compensation and transcriptional adaptation. To apply, candidates should submit a CV, a short statement of research experience and interests (maximum 2 pages), and the names and contact information for 2-3 references to Prof. Didier Stainier at [email protected]. Applications should also be submitted through the International Max Planck Research School for Molecular Organ Biology (IMPRS-MOB). For further details, visit the institute's website or contact the lab directly. The Max Planck Society is committed to diversity and encourages applications from all backgrounds, including individuals with disabilities. This opportunity is ideal for students interested in genetic compensation, transcriptional adaptation, RNA/protein biochemistry, and developmental genetics.

The Max Planck Institute for Heart and Lung Research in Bad Nauheim, Germany, is offering a PhD position in RNA/protein biochemistry and molecular biology, focusing on the study of genetic compensation and transcriptional adaptation. The research is based in the Department of Developmental Genetics (Stainier lab) and investigates the molecular and cellular mechanisms underlying cardiovascular and pulmonary diseases. The project centers on the phenomenon of transcriptional adaptation, where mutant mRNA decay fragments modulate the expression of related genes, leading to phenotypic rescue. This research utilizes model organisms such as zebrafish, mouse, C. elegans, and humans, and leverages cutting-edge technologies and core facilities in sequencing, proteomics, bioinformatics, cytometry, microscopy, and small animal imaging. Applicants should have a Master's degree in biology, biochemistry, genetics, or a related field, with a strong background in molecular biology and RNA/protein biochemistry. Experience with zebrafish, mouse, or C. elegans is advantageous. The institute values diversity and encourages applications from all backgrounds, including individuals with disabilities. The position provides an interdisciplinary and international research environment, with access to state-of-the-art facilities and support for young researchers. To apply, candidates should submit a CV, names and contact information for 2-3 references, and a short statement of research experience and interests to Prof. Didier Stainier at [email protected]. Additionally, applications should be submitted to the International Max Planck Research School for Molecular Organ Biology (IMPRS-MOB). For more information, visit the provided website links. Key research areas include genetic compensation, transcriptional adaptation, RNA and protein biochemistry, molecular biology, developmental genetics, and gene expression. The position is ideal for candidates passionate about genetic research and eager to contribute to a rapidly developing field with significant implications for understanding disease mechanisms.